| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dimodular nonribosomal peptide synthase |
Protein Synonyms/Alias | |
Gene Name | dhbF |
Gene Synonyms/Alias | BSU31960 |
Created Date | 3-June-2014 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Phosphorylation | Position | Peptide | Code | Type | References | | 996 | FFELGGHSLLAARLM | S | HTP | [1],UniProt | | 988 | ARVGIDDSFFELGGH | S | HTP | [1] | |
Reference | [1]The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Macek B,Mijakovic I,Olsen JV,Gnad F,Kumar C,Jensen PR,Mann M Mol. Cell Proteomics 2007, Apr;6(4):697-707. [ PMID:17218307] |
Functional Description From UniProt | FUNCTION: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains |
| MOD_RES 996 996 O-(pantetheine 4'-phosphoryl)serine
MOD_RES 2071 2071 O-(pantetheine 4'-phosphoryl)serine (Potential) |
| Completeproteome; Ligase; Phosphopantetheine; Phosphoprotein; Referenceproteome; Repeat |
Protein Sequence | MPDTKDLQYS LTGAQTGIWF AQQLDPDNPI YNTAEYIEIN GPVNIALFEE ALRHVIKEAE 60
SLHVRFGENM DGPWQMINPS PDVQLHVIDV SSEPDPEKTA LNWMKADLAK PVDLGYAPLF 120
NEALFIAGPD RFFWYQRIHH IAIDGFGFSL IAQRVASTYT ALIKGQTAKS RSFGSLQAIL 180
EEDTDYRGSE QYEKDRQFWL DRFADAPEVV SLADRAPRTS NSFLRHTAYL PPSDVNALKE 240
AARYFSGSWH EVMIAVSAVY VHRMTGSEDV VLGLPMMGRI GSASLNVPAM VMNLLPLRLT 300
VSSSMSFSEL IQQISREIRS IRRHHKYRHE ELRRDLKLIG ENHRLFGPQI NLMPFDYGLD 360
FAGVRGTTHN LSAGPVDDLS INVYDRTDGS GLRIDVDANP EVYSESDIKL HQQRILQLLQ 420
TASAGEDMLI GQMELLLPEE KEKVISKWNE TAKSEKLVSL QDMFEKQAVL TPERIALMCD 480
DIQVNYRKLN EEANRLARLL IEKGIGPEQF VALALPRSPE MVASMLGVLK TGAAYLPLDP 540
EFPADRISYM LEDAKPSCII TTEEIAASLP DDLAVPELVL DQAVTQEIIK RYSPENQDVS 600
VSLDHPAYII YTSGSTGRPK GVVVTQKSLS NFLLSMQEAF SLGEEDRLLA VTTVAFDISA 660
LELYLPLISG AQIVIAKKET IREPQALAQM IENFDINIMQ ATPTLWHALV TSEPEKLRGL 720
RVLVGGEALP SGLLQELQDL HCSVTNLYGP TETTIWSAAA FLEEGLKGVP PIGKPIWNTQ 780
VYVLDNGLQP VPPGVVGELY IAGTGLARGY FHRPDLTAER FVADPYGPPG TRMYRTGDQA 840
RWRADGSLDY IGRADHQIKI RGFRIELGEI DAVLANHPHI EQAAVVVRED QPGDKRLAAY 900
VVADAAIDTA ELRRYMGASL PDYMVPSAFV EMDELPLTPN GKLDRKALPA PDFSTSVSDR 960
APRTPQEEIL CDLFAEVLGL ARVGIDDSFF ELGGHSLLAA RLMSRIREVM GAELGIAKLF 1020
DEPTVAGLAA HLDLAQSACP ALQRAERPEK IPLSFAQRRL WFLHCLEGPS PTYNIPVAVR 1080
LSGELDQGLL KAALYDLVCR HESLRTIFPE SQGTSYQHIL DADRACPELH VTEIAEKELS 1140
DRLAEAVRYS FDLAAEPAFR AELFVIGPDE YVLLLLVHHI VGDGWSLTPL TRDLGTAYAA 1200
RCHGRSPEWA PLAVQYADYA LWQQELLGNE DDPNSLIAGQ LAFWKETLKN LPDQLELPTD 1260
YSRPAEPSHD GDTIHFRIEP EFHKRLQELA RANRVSLFMV LQSGLAALLT RLGAGTDIPI 1320
GSPIAGRNDD ALGDLVGLFI NTLVLRTDTS GDPSFRELLD RVREVNLAAY DNQDLPFERL 1380
VEVLNPARSR ATHPLFQIML AFQNTPDAEL HLPDMESSLR INSVGSAKFD LTLEISEDRL 1440
ADGTPNGMEG LLEYSTDLFK RETAQALADR LMRLLEAAES DPDEQIGNLD ILAPEEHSSM 1500
VTDWQSVSEK IPHACLPEQF EKQAALRPDA IAVVYENQEL SYAELNERAN RLARMMISEG 1560
VGPEQFVALA LPRSLEMAVG LLAVLKAGAA YLPLDPDYPA DRIAFMLKDA QPAFIMTNTK 1620
AANHIPPVEN VPKIVLDDPE LAEKLNTYPA GNPKNKDRTQ PLSPLNTAYV IYTSGSTGVP 1680
KGVMIPHQNV TRLFAATEHW FRFSSGDIWT MFHSYAFDFS VWEIWGPLLH GGRLVIVPHH 1740
VSRSPEAFLR LLVKEGVTVL NQTPSAFYQF MQAEREQPDL GQALSLRYVI FGGEALELSR 1800
LEDWYNRHPE NRPQLINMYG ITETTVHVSY IELDRSMAAL RANSLIGCGI PDLGVYVLDE 1860
RLQPVPPGVA GELYVSGAGL ARGYLGRPGL TSERFIADPF GPPGTRMYRT GDVARLRADG 1920
SLDYVGRADH QVKIRGFRIE LGEIEAALVQ HPQLEDAAVI VREDQPGDKR LAAYVIPSEE 1980
TFDTAELRRY AAERLPDYMV PAAFVTMKEL PLTPNGKLDR KALPAPDFAA AVTGRGPRTP 2040
QEEILCDLFM EVLHLPRVGI DDRFFDLGGH SLLAVQLMSR IREALGVELS IGNLFEAPTV 2100
AGLAERLEMG SSQSALDVLL PLRTSGDKPP LFCVHPAGGL SWCYAGLMTN IGTDYPIYGL 2160
QARGIGQREE LPKTLDDMAA DYIKQIRTVQ PKGPYHLLGW SLGGNVVQAM ATQLQNQGEE 2220
VSLLVMLDAY PNHFLPIKEA PDDEEALIAL LALGGYDPDS LGEKPLDFEA AIEILRRDGS 2280
ALASLDETVI LNLKNTYVNS VGILGSYKPK TFRGNVLFFR STIIPEWFDP IEPDSWKPYI 2340
NGQIEQIDID CRHKDLCQPE PLAQIGKVLA VKLEELNK 2378 |
| GO:0016788 F:hydrolase activity, acting on ester bonds IEA:InterPro GO:0016874 F:ligase activity IEA:UniProtKB-KW GO:0031177 F:phosphopantetheine binding IEA:InterPro GO:0009058 P:biosynthetic process IEA:InterPro |
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