| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphocarrier protein HPr |
Protein Synonyms/Alias | |
Gene Name | ptsH |
Gene Synonyms/Alias | SMU_674 |
Created Date | 3-June-2014 |
Organism | Streptococcus mutans serotype c (strain ATCC 700610 / UA159) |
NCBI Taxa ID | 210007 |
Phosphorylation | Position | Peptide | Code | Type | References | | 46 | GKAVNLKSIMGVMSL | S | LTP | [1] | |
Reference | [1]Seryl-phosphorylated HPr regulates CcpA-independent carbon catabolite repression in conjunction with PTS permeases in Streptococcus mutans. Zeng L,Burne RA Mol. Microbiol. 2010, Mar;75(5):1145-58. [ PMID:20487301] |
Functional Description From UniProt | FUNCTION: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III) |
| MOD_RES 46 46 Phosphoserine; by HPrK/P (By similarity) |
| Completeproteome; Cytoplasm; Directproteinsequencing; Kinase; Phosphoprotein; Phosphotransferasesystem; Serine/threonine-proteinkinase; Sugartransport; Transcription; Transcriptionregulation; Transferase; Transport |
Protein Sequence | MASKDFHIVA ETGIHARPAT LLVQTASKFA SDITLDYKGK AVNLKSIMGV MSLGVGQGAD 60
VTITAEGADA DDAIAAINET MTKEGLA 87 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0004674 F:protein serine/threonine kinase activity IEA:UniProtKB-KW GO:0005351 F:sugar:hydrogen symporter activity IEA:InterPro GO:0009401 P:phosphoenolpyruvate-dependent sugar phosphotransferase system IEA:UniProtKB-KW GO:0006355 P:regulation of transcription, DNA-templated IEA:UniProtKB-KW GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
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