| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphotransferase RcsD |
Protein Synonyms/Alias | |
Gene Name | rcsD |
Gene Synonyms/Alias | yojN, yojP, yojQ; OrderedLocusNames=b2216, JW2204 |
Created Date | 3-June-2014 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Phosphorylation | Position | Peptide | Code | Type | References | | 880 | PGIEKYISDIDSYVK | S | HTP | [1] | | 842 | AALAQTAHRLKGVFA | H | LTP | [2],UniProt | |
Reference | [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium. Soares NC,Spät P,Krug K,Macek B J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [ PMID:23590516] [2]A novel feature of the multistep phosphorelay in Escherichia coli: a revised model of the RcsC --> YojN --> RcsB signalling pathway implicated in capsular synthesis and swarming behaviour. Takeda S,Fujisawa Y,Matsubara M,Aiba H,Mizuno T Mol. Microbiol. 2001, Apr;40(2):440-50. [ PMID:11309126] |
Functional Description From UniProt | FUNCTION: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division |
| TRANSMEM 22 42 Helical; (Potential)
TRANSMEM 309 329 Helical; (Potential)
MOD_RES 842 842 Phosphohistidine |
| 3D-structure; ATP-binding; Cellinnermembrane; Cellmembrane; Completeproteome; Kinase; Membrane; Nucleotide-binding; Phosphoprotein; Referenceproteome; Transferase; Transmembrane; Transmembranehelix; Two-componentregulatorysystem |
Protein Sequence | MRQKETTATT RFSLLPGSIT RFFLLLIIVL LVTMGVMVQS AVNAWLKDKS YQIVDITHAI 60
QKRVDNWRYV TWQIYDNIAA TTSPSSGEGL QETRLKQDVY YLEKPRRKTE ALIFGSHDNS 120
TLEMTQRMST YLDTLWGAEN VPWSMYYLNG QDNSLVLIST LPLKDLTSGF KESTVSDIVD 180
SRRAEMLQQA NALDERESFS NMRRLAWQNG HYFTLRTTFN QPGHLATVVA FDLPINDLIP 240
PGMPLDSFRL EPDATATGNN DNEKEGTDSV SIHFNSTKIE ISSALNSTDM RLVWQVPYGT 300
LLLDTLQNIL LPLLLNIGLL ALALFGYTTF RHFSSRSTEN VPSTAVNNEL RILRAINEEI 360
VSLLPLGLLV HDQESNRTVI SNKIADHLLP HLNLQNITTM AEQHQGIIQA TINNELYEIR 420
MFRSQVAPRT QIFIIRDQDR EVLVNKKLKQ AQRLYEKNQQ GRMIFMKNIG DALKEPAQSL 480
AESAAKLNAP ESKQLANQAD VLVRLVDEIQ LANMLADDSW KSETVLFSVQ DLIDEVVPSV 540
LPAIKRKGLQ LLINNHLKAH DMRRGDRDAL RRILLLLMQY AVTSTQLGKI TLEVDQDESS 600
EDRLTFRILD TGEGVSIHEM DNLHFPFINQ TQNDRYGKAD PLAFWLSDQL ARKLGGHLNI 660
KTRDGLGTRY SVHIKMLAAD PEVEEEEERL LDDVCVMVDV TSAEIRNIVT RQLENWGATC 720
ITPDERLISQ DYDIFLTDNP SNLTASGLLL SDDESGVREI GPGQLCVNFN MSNAMQEAVL 780
QLIEVQLAQE EVTESPLGGD ENAQLHASGY YALFVDTVPD DVKRLYTEAA TSDFAALAQT 840
AHRLKGVFAM LNLVPGKQLC ETLEHLIREK DVPGIEKYIS DIDSYVKSLL 890 |
| GO:0005887 C:integral component of plasma membrane IDA:EcoCyc GO:0005524 F:ATP binding IEA:UniProtKB-KW GO:0009927 F:histidine phosphotransfer kinase activity IMP:EcoCyc GO:0000160 P:phosphorelay signal transduction system IMP:EcoCyc |
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