※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional regulator CtsR
Protein Synonyms/Alias
 
Gene Name
 ctsR
Gene Synonyms/Alias
 yacG; OrderedLocusNames=BSU00830
Created Date
 3-June-2014
Organism
 Bacillus subtilis (strain 168)
NCBI Taxa ID
 224308
Phosphorylation
Position
Peptide
Code
Type
References
52 YVINTRFTSERGYIV T HTP [1]
15 IIEQYLKRVLDQNGK R HTP [1]
57 RFTSERGYIVESKRG Y HTP [1]
61 ERGYIVESKRGGGGY S HTP [1]
53 VINTRFTSERGYIVE S HTP [1]
55 NTRFTSERGYIVESK R HTP [1]
Reference
 [1]Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
 Elsholz AK,Turgay K,Michalik S,Hessling B,Gronau K,Oertel D,Mäder U,Bernhardt J,Becher D,Hecker M,Gerth U
 Proc. Natl. Acad. Sci. U.S.A. 2012, May, 8;109(19):7451-6. [PMID:22517742]
Functional Description From UniProt
 FUNCTION: Controls the expression of the cellular protein quality control genes clpC, clpE and clpP. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock, CtsR is degraded by the ClpCP and ClpEP proteolytic systems, ensuring the derepression of clpE, clpP and the clpC operon. CtsR negatively autoregulates its own synthesis
Sequence Annotation From UniProt
 
Key Word From UniProt
 Completeproteome; DNA-binding; Referenceproteome; Repressor; Stressresponse; Transcription; Transcriptionregulation
Protein Sequence
 MGHNISDIIE QYLKRVLDQN GKEILEIKRS EIADKFQCVP SQINYVINTR FTSERGYIVE 60
 SKRGGGGYIR IIKIKMNNEV VLINNIISQI NTHLSQAASD DIILRLLEDK VISEREAKMM 120
 VSVMDRSVLH IDLPERDELR ARMMKAMLTS LKLK 154
  GO:0003677   F:DNA binding IEA:UniProtKB-KW
  GO:0006355   P:regulation of transcription, DNA-templated IEA:UniProtKB-KW
  GO:0006950   P:response to stress IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR008463   CtsR.
  PF05848   CtsR.