Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcriptional regulator CtsR |
Protein Synonyms/Alias | |
Gene Name | ctsR |
Gene Synonyms/Alias | yacG; OrderedLocusNames=BSU00830 |
Created Date | 3-June-2014 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Phosphorylation | Position | Peptide | Code | Type | References | 52 | YVINTRFTSERGYIV | T | HTP | [1] | 15 | IIEQYLKRVLDQNGK | R | HTP | [1] | 57 | RFTSERGYIVESKRG | Y | HTP | [1] | 61 | ERGYIVESKRGGGGY | S | HTP | [1] | 53 | VINTRFTSERGYIVE | S | HTP | [1] | 55 | NTRFTSERGYIVESK | R | HTP | [1] | |
Reference | [1]Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis. Elsholz AK,Turgay K,Michalik S,Hessling B,Gronau K,Oertel D,Mäder U,Bernhardt J,Becher D,Hecker M,Gerth U Proc. Natl. Acad. Sci. U.S.A. 2012, May, 8;109(19):7451-6. [ PMID:22517742] |
Functional Description From UniProt | FUNCTION: Controls the expression of the cellular protein quality control genes clpC, clpE and clpP. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock, CtsR is degraded by the ClpCP and ClpEP proteolytic systems, ensuring the derepression of clpE, clpP and the clpC operon. CtsR negatively autoregulates its own synthesis |
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| Completeproteome; DNA-binding; Referenceproteome; Repressor; Stressresponse; Transcription; Transcriptionregulation |
Protein Sequence | MGHNISDIIE QYLKRVLDQN GKEILEIKRS EIADKFQCVP SQINYVINTR FTSERGYIVE 60 SKRGGGGYIR IIKIKMNNEV VLINNIISQI NTHLSQAASD DIILRLLEDK VISEREAKMM 120 VSVMDRSVLH IDLPERDELR ARMMKAMLTS LKLK 154 |
| GO:0003677 F:DNA binding IEA:UniProtKB-KW GO:0006355 P:regulation of transcription, DNA-templated IEA:UniProtKB-KW GO:0006950 P:response to stress IEA:UniProtKB-KW GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
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