※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pantothenate synthetase
Protein Synonyms/Alias
 PS
Gene Name
 panC
Gene Synonyms/Alias
 b0133, JW0129
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
187 AKDGLALSSRNGYLT S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; ATP-binding; Completeproteome; Cytoplasm; Ligase; Nucleotide-binding; Pantothenatebiosynthesis; Referenceproteome
Protein Sequence
 MLIIETLPLL RQQIRRLRME GKRVALVPTM GNLHDGHMKL VDEAKARADV VVVSIFVNPM 60
 QFDRPEDLAR YPRTLQEDCE KLNKRKVDLV FAPSVKEIYP NGTETHTYVD VPGLSTMLEG 120
 ASRPGHFRGV STIVSKLFNL VQPDIACFGE KDFQQLALIR KMVADMGFDI EIVGVPIMRA 180
 KDGLALSSRN GYLTAEQRKI APGLYKVLSS IADKLQAGER DLDEIITIAG QELNEKGFRA 240
 DDIQIRDADT LLEVSETSKR AVILVAAWLG DARLIDNKMV ELA 283
  GO:0005829   C:cytosol IDA:UniProtKB
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0042802   F:identical protein binding IPI:IntAct
  GO:0004592   F:pantoate-beta-alanine ligase activity IDA:EcoCyc
  GO:0033317   P:pantothenate biosynthetic process from valine IMP:EcoCyc
  IPR004821   Cyt_trans-like.
  IPR003721   Pantoate_ligase.
  IPR014729   Rossmann-like_a/b/a_fold.
  PF02569   Pantoate_ligase.