※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alginate biosynthesis transcriptional regulatory protein AlgB
Protein Synonyms/Alias
 
Gene Name
 algB
Gene Synonyms/Alias
 PA5483
Created Date
 3-June-2014
Organism
 Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
NCBI Taxa ID
 208964
Phosphorylation
Position
Peptide
Code
Type
References
59 VFDLCFLDLRLGEDN D LTP [1],UniProt
Reference
 [1]Phosphorylation-independent activity of the response regulators AlgB and AlgR in promoting alginate biosynthesis in mucoid Pseudomonas aeruginosa.
 Ma S,Selvaraj U,Ohman DE,Quarless R,Hassett DJ,Wozniak DJ
 J. Bacteriol. 1998, Feb;180(4):956-68. [PMID:9473053]
Functional Description From UniProt
 FUNCTION: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD
Sequence Annotation From UniProt
 MOD_RES 59 59 4-aspartylphosphate
Key Word From UniProt
 Activator; Alginatebiosynthesis; ATP-binding; Completeproteome; DNA-binding; Nucleotide-binding; Phosphoprotein; Referenceproteome; Transcription; Transcriptionregulation; Two-componentregulatorysystem
Protein Sequence
 METTSEKQGR ILLVDDESAI LRTFRYCLED EGYSVATASS APQAEALLQR QVFDLCFLDL 60
 RLGEDNGLDV LAQMRVQAPW MRVVIVTAHS AVDTAVDAMQ AGAVDYLVKP CSPDQLRLAA 120
 AKQLEVRQLT ARLEALEDEV RRQGDGLESH SPAMAAVLET ARQVAATDAN ILILGESGSG 180
 KGELARAIHT WSKRAKKPQV TINCPSLTAE LMESELFGHS RGAFTGATES TLGRVSQADG 240
 GTLFLDEIGD FPLTLQPKLL RFIQDKEYER VGDPVTRRAD VRILAATNRD LGAMVAQGQF 300
 REDLLYRLNV IVLNLPPLRE RAEDILGLAE RFLARFVKDY GRPARGFSEA AREAMRQYPW 360
 PGNVRELRNV IERASIICNQ ELVDVDHLGF SAAQSASSAP RIGESLSLED LEKAHITAVM 420
 ASSATLDQAA KTLGIDASTL YRKRKQYGL 449
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0017111   F:nucleoside-triphosphatase activity IEA:InterPro
  GO:0016791   F:phosphatase activity IDA:PseudoCAP
  GO:0000156   F:phosphorelay response regulator activity IDA:PseudoCAP
  GO:0000155   F:phosphorelay sensor kinase activity IDA:PseudoCAP
  GO:0043565   F:sequence-specific DNA binding IEA:InterPro
  GO:0044212   F:transcription regulatory region DNA binding IDA:PseudoCAP
  GO:0042121   P:alginic acid biosynthetic process IMP:PseudoCAP
  GO:0016311   P:dephosphorylation IDA:GOC
  GO:0035556   P:intracellular signal transduction IDA:GOC
  GO:1900232   P:negative regulation of single-species biofilm formation on inanimate substrate IMP:PseudoCAP
  GO:2000147   P:positive regulation of cell motility IMP:PseudoCAP
  GO:0045862   P:positive regulation of proteolysis IMP:PseudoCAP
  GO:1900378   P:positive regulation of secondary metabolite biosynthetic process IMP:PseudoCAP
  GO:0045893   P:positive regulation of transcription, DNA-templated IMP:PseudoCAP
  GO:0023014   P:signal transduction by phosphorylation IDA:GOC
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR003593   AAA+_ATPase.
  IPR011006   CheY-like_superfamily.
  IPR009057   Homeodomain-like.
  IPR002197   HTH_Fis.
  IPR027417   P-loop_NTPase.
  IPR001789   Sig_transdc_resp-reg_receiver.
  IPR002078   Sigma_54_int.
  IPR025662   Sigma_54_int_dom_ATP-bd_1.
  IPR025943   Sigma_54_int_dom_ATP-bd_2.
  IPR025944   Sigma_54_int_dom_CS.
  PF02954   HTH_8.
  PF00072   Response_reg.
  PF00158   Sigma54_activat.
  SM00382   AAA.
  SM00448   REC.
  PS50110   RESPONSE_REGULATORY.
  PS00675   SIGMA54_INTERACT_1.
  PS00676   SIGMA54_INTERACT_2.
  PS00688   SIGMA54_INTERACT_3.
  PS50045   SIGMA54_INTERACT_4.