※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoserine aminotransferase
Protein Synonyms/Alias
 PSAT
Gene Name
 serC
Gene Synonyms/Alias
 pdxC, pdxF; OrderedLocusNames=b0907, JW0890
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
101 ADYVDAGYWAASAIK Y HTP [1]
8 MAQIFNFSSGPAMLP S HTP [1]
65 RDLLNVPSNYKVLFC S HTP [1]
9 AQIFNFSSGPAMLPA S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. Is involved in both pyridoxine and serine biosynthesis
Sequence Annotation From UniProt
 MOD_RES 198 198 N6-(pyridoxal phosphate)lysine
Key Word From UniProt
 3D-structure; Amino-acidbiosynthesis; Aminotransferase; Completeproteome; Cytoplasm; Directproteinsequencing; Pyridoxalphosphate; Pyridoxinebiosynthesis; Referenceproteome; Serinebiosynthesis; Transferase
Protein Sequence
 MAQIFNFSSG PAMLPAEVLK QAQQELRDWN GLGTSVMEVS HRGKEFIQVA EEAEKDFRDL 60
 LNVPSNYKVL FCHGGGRGQF AAVPLNILGD KTTADYVDAG YWAASAIKEA KKYCTPNVFD 120
 AKVTVDGLRA VKPMREWQLS DNAAYMHYCP NETIDGIAID ETPDFGADVV VAADFSSTIL 180
 SRPIDVSRYG VIYAGAQKNI GPAGLTIVIV REDLLGKANI ACPSILDYSI LNDNGSMFNT 240
 PPTFAWYLSG LVFKWLKANG GVAEMDKINQ QKAELLYGVI DNSDFYRNDV AKANRSRMNV 300
 PFQLADSALD KLFLEESFAA GLHALKGHRV VGGMRASIYN AMPLEGVKAL TDFMVEFERR 360
 HG 362
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0004648   F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity IDA:EcoCyc
  GO:0030170   F:pyridoxal phosphate binding IDA:EcoCyc
  GO:0006564   P:L-serine biosynthetic process IMP:EcoCyc
  GO:0006563   P:L-serine metabolic process IGI:UniProtKB
  GO:0042823   P:pyridoxal phosphate biosynthetic process IMP:EcoCyc
  GO:0008615   P:pyridoxine biosynthetic process IEA:UniProtKB-HAMAP
  IPR000192   Aminotrans_V/Cys_dSase.
  IPR020578   Aminotrans_V_PyrdxlP_BS.
  IPR022278   Pser_aminoTfrase.
  IPR003248   Pser_aminoTfrase_subgr.
  IPR015424   PyrdxlP-dep_Trfase.
  IPR015421   PyrdxlP-dep_Trfase_major_sub1.
  IPR015422   PyrdxlP-dep_Trfase_major_sub2.
  PF00266   Aminotran_5.
  PS00595   AA_TRANSFER_CLASS_5.