Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor 2 |
Protein Synonyms/Alias | EF-2 |
Gene Name | fusA |
Gene Synonyms/Alias | fus; OrderedLocusNames=Saci_0603 |
Created Date | 3-June-2014 |
Organism | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) |
NCBI Taxa ID | 330779 |
Phosphorylation | Position | Peptide | Code | Type | References | 487 | SQVFEGKSPNKHNKL | S | HTP | [1] | 159 | LIKELKLSSQEIQKR | S | HTP | [1] | 480 | RESIRNKSQVFEGKS | S | HTP | [1] | 160 | IKELKLSSQEIQKRL | S | HTP | [1] | |
Reference | [1]Archaeal signal transduction: impact of protein phosphatase deletions on cell size, motility, and energy metabolism in Sulfolobus acidocaldarius. Reimann J,Esser D,Orell A,Amman F,Pham TK,Noirel J,Lindås AC,Bernander R,Wright PC,Siebers B,Albers SV Mol. Cell Proteomics 2013, Dec;12(12):3908-23. [ PMID:24078887] |
Functional Description From UniProt | FUNCTION: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) |
| MOD_RES 604 604 Diphthamide (By similarity) |
| Completeproteome; Cytoplasm; Directproteinsequencing; Elongationfactor; GTP-binding; Nucleotide-binding; Proteinbiosynthesis |
Protein Sequence | MPRYKTVEQV LSLMKDVTRV RNIGIIAHVD HGKTTTSDTL LAASGIISQK VAGEALALDY 60 LSVEQQRGIT VKAANISLYH EIDGKGYVIN LIDTPGHVDF SGRVTRSLRV LDGSIVVIDA 120 VEGIMTQTET VLRQSLEERV RPILFINKVD RLIKELKLSS QEIQKRLIDL IIEVNNLIET 180 YGEPEFKDQW KIKPELGNVV FGSAKDKWGF SVPMAGKRGV KFSDVVNAYT SGDKAKIEEL 240 ASKVPIHEAL LDAVIKFVPN PRDSQKYRIP KIWKGDLDSE IAKAMINADP NGPIVMMIND 300 MKVDPHAGLV ATGRVFSGTL RAGEEVWLVN AKRQQRILQV SLYMGAIREL AEEIPVGNIA 360 AALGMDAARS GETGVDIRFK DSVLGSFEKL HYISEPVVTI SVEPRNPKDL TKMIDALRKL 420 SIEDSNLVVK INEETGEYLL SGMGFLHLEV SLQLLKENYG LDVVTTPPIV VYRESIRNKS 480 QVFEGKSPNK HNKLYISVEP LNNQTIDLIA NGTIKEDMDN KEMAKILRDQ AEWDYDEAKK 540 IVAIDENINV FIDATSGVQH LREIMDTLLQ GFRLAMKEGP LAFEPVRGVK VVLHDAVVHE 600 DPAHRGPAQL YPAVRNAIFA GILTSKPTLL EPLQKLDIRI PMEYLGNVTA VITRKRGKVI 660 NVVQTGNVAR VYAEIPVGES FELASELRAS SAGRAFWGTE FSRWAPVPDS ILVDLIMKIR 720 ERKGKPKQLP KVEDFIS 737 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0005525 F:GTP binding IEA:UniProtKB-HAMAP GO:0003924 F:GTPase activity IEA:InterPro GO:0003746 F:translation elongation factor activity IEA:UniProtKB-HAMAP |
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