| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Biotin sulfoxide reductase |
Protein Synonyms/Alias | BDS reductase; BSO reductase; Met-S-SO reductase |
Gene Name | bisC |
Gene Synonyms/Alias | b3551, JW5940 |
Created Date | 3-June-2014 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Phosphorylation | Position | Peptide | Code | Type | References | | 115 | ASIFAGSYGWRSNGV | Y | HTP | [1] | |
Reference | [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence. Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A PLoS Pathog. 2013;9(6):e1003403. [ PMID:23785281] |
Functional Description From UniProt | FUNCTION: This enzyme may serve as a scavenger, allowing the cell to utilize biotin sulfoxide as a biotin source. It reduces a spontaneous oxidation product of biotin, D-biotin D-sulfoxide (BSO or BDS), back to biotin. Also exhibits methionine-(S)-sulfoxide (Met-S-SO) reductase activity, acting specifically on the (S) enantiomer in the free, but not the protein-bound form. It thus plays a role in assimilation of oxidized methionines |
| |
| Completeproteome; Metal-binding; Molybdenum; Oxidoreductase; Referenceproteome |
Protein Sequence | MANSSSRYSV LTAAHWGPML VETDGETVFS SRGALATGME NSLQSAVRDQ VHSNTRVRFP 60
MVRKGFLASP ENPQGIRGQD EFVRVSWDEA LDLIHQQHKR IREAYGPASI FAGSYGWRSN 120
GVLHKASTLL QRYMALAGGY TGHLGDYSTG AAQAIMPYVV GGSEVYQQQT SWPLVLEHSD 180
VVVLWSANPL NTLKIAWNAS DEQGLSYFSA LRDSGKKLIC IDPMRSETVD FFGDKMEWVA 240
PHMGTDVALM LGIAHTLVEN GWHDEAFLAR CTTGYAVFAS YLLGESDGIA KTAEWAAEIC 300
GVGAAKIREL AAIFHQNTTM LMAGWGMQRQ QFGEQKHWMI VTLAAMLGQI GTPGGGFGLS 360
YHFANGGNPT RRSAVLSSMQ GSLPGGCDAV DKIPVARIVE ALENPGGAYQ HNGMNRHFPD 420
IRFIWWAGGA NFTHHQDTNR LIRAWQKPEL VVISECFWTA AAKHADIVLP ATTSFERNDL 480
TMTGDYSNQH LVPMKQVVPP RYEARNDFDV FAELSERWEK GGYARFTEGK SELQWLETFY 540
NVARQRGASQ QVELPPFAEF WQANQLIEMP ENPDSERFIR FADFCRDPLA HPLKTASGKI 600
EIFSQRIADY GYPDCPGHPM WLEPDEWQGN AEPEQLQVLS AHPAHRLHSQ LNYSSLRELY 660
AVANREPVTI HPDDAQERGI QDGDTVRLWN ARGQILAGAV ISEGIKPGVI CIHEGAWPDL 720
DLTADGICKN GAVNVLTKDL PSSRLGNGCA GNTALAWLEK YNGPELTLTA FEPPASS 777 |
| GO:0016020 C:membrane IBA:RefGenome GO:0009055 F:electron carrier activity IEA:InterPro GO:0033744 F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity IDA:EcoCyc GO:0030151 F:molybdenum ion binding IMP:EcoCyc GO:0045333 P:cellular respiration IBA:RefGenome |
| |
| |
| |
| |
| |
