※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein TolA
Protein Synonyms/Alias
 
Gene Name
 tolA
Gene Synonyms/Alias
 cim, excC, lky; OrderedLocusNames=b0739, JW0729
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
69 EQYKRMQSQESSAKR S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3, and K). Necessary for the colicins to reach their respective targets after initial binding to the bacteria. Also involved in the translocation of bacteriophage DNA
Sequence Annotation From UniProt
 TRANSMEM 14 34 Helical; (Potential)
 DISULFID 363 388
Key Word From UniProt
 3D-structure; Bacteriocintransport; Cellinnermembrane; Cellmembrane; Completeproteome; Disulfidebond; Membrane; Proteintransport; Referenceproteome; Repeat; Transmembrane; Transmembranehelix; Transport
Protein Sequence
 MSKATEQNDK LKRAIIISAV LHVILFAALI WSSFDENIEA SAGGGGGSSI DAVMVDSGAV 60
 VEQYKRMQSQ ESSAKRSDEQ RKMKEQQAAE ELREKQAAEQ ERLKQLEKER LAAQEQKKQA 120
 EEAAKQAELK QKQAEEAAAK AAADAKAKAE ADAKAAEEAA KKAAADAKKK AEAEAAKAAA 180
 EAQKKAEAAA AALKKKAEAA EAAAAEARKK AATEAAEKAK AEAEKKAAAE KAAADKKAAA 240
 EKAAADKKAA EKAAAEKAAA DKKAAAEKAA ADKKAAAAKA AAEKAAAAKA AAEADDIFGE 300
 LSSGKNAPKT GGGAKGNNAS PAGSGNTKNN GASGADINNY AGQIKSAIES KFYDASSYAG 360
 KTCTLRIKLA PDGMLLDIKP EGGDPALCQA ALAAAKLAKI PKPPSQAVYE VFKNAPLDFK 420
 P 421
  GO:0016021   C:integral component of membrane IDA:EcoliWiki
  GO:0005886   C:plasma membrane IDA:EcoliWiki
  GO:0005215   F:transporter activity IEA:InterPro
  GO:0043213   P:bacteriocin transport IMP:EcoliWiki
  GO:0017038   P:protein import IMP:EcoliWiki
  IPR014161   Tol-Pal_TolA.
  PF06519   TolA.