※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable fructose-bisphosphate aldolase
Protein Synonyms/Alias
 FBP aldolase;  FBPA
Gene Name
 fbaA
Gene Synonyms/Alias
 fba, fba1, tsr; OrderedLocusNames=BSU37120
Created Date
 3-June-2014
Organism
 Bacillus subtilis (strain 168)
NCBI Taxa ID
 224308
Phosphorylation
Position
Peptide
Code
Type
References
234 TAKINVNTENQISSA T HTP [1],UniProt
50 SPVILGVSEGAGRYM S HTP [2]
212 PLVLHGGTGIPTADI T HTP [2],UniProt
Reference
 [1]Stable isotope labeling by amino acids in cell culture (SILAC) applied to quantitative proteomics of Bacillus subtilis.
 Soufi B,Kumar C,Gnad F,Mann M,Mijakovic I,Macek B
 J. Proteome Res. 2010, Jul, 2;9(7):3638-46. [PMID:20509597]
 [2]Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence.
 Misra SK,Milohanic E,Aké F,Mijakovic I,Deutscher J,Monnet V,Henry C
 Proteomics 2011, Nov;11(21):4155-65. [PMID:21956863]
Functional Description From UniProt
 FUNCTION: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity)
Sequence Annotation From UniProt
 MOD_RES 212 212 Phosphothreonine
 MOD_RES 234 234 Phosphothreonine
Key Word From UniProt
 Completeproteome; Directproteinsequencing; Glycolysis; Lyase; Metal-binding; Phosphoprotein; Referenceproteome; Sporulation; Zinc
Protein Sequence
 MPLVSMTEML NTAKEKGYAV GQFNLNNLEF TQAILQAAEE EKSPVILGVS EGAGRYMGGF 60
 KTVVAMVKAL MEEYKVTVPV AIHLDHGSSF ESCAKAIHAG FTSVMIDASH HPFEENVATT 120
 AKVVELAHFH GVSVEAELGT VGGQEDDVIA EGVIYADPKE CQELVERTGI DCLAPALGSV 180
 HGPYKGEPNL GFKEMEEIGK STGLPLVLHG GTGIPTADIK KSISLGTAKI NVNTENQISS 240
 AKAVRETLAA KPDEYDPRKY LGPAREAIKE TVIGKMREFG SSNQA 285
  GO:0004332   F:fructose-bisphosphate aldolase activity IEA:UniProtKB-EC
  GO:0008270   F:zinc ion binding IEA:InterPro
  GO:0030388   P:fructose 1,6-bisphosphate metabolic process IEA:InterPro
  GO:0006096   P:glycolytic process IEA:UniProtKB-UniPathway
  GO:0030435   P:sporulation resulting in formation of a cellular spore IEA:UniProtKB-KW
  IPR013785   Aldolase_TIM.
  IPR011289   Fruc_bis_ald_class-2.
  IPR000771   Ketose_bisP_aldolase_II.
  PF01116   F_bP_aldolase.
  PS00602   ALDOLASE_CLASS_II_1.
  PS00806   ALDOLASE_CLASS_II_2.