UniProt Accession

 GATZ_ECOLI;  P0C8J8;  P37191;  P76414

Genbank Protein ID

 U00096;  AP009048

Genbank Nucleotide ID

 AAC75156.1;  BAA15965.1

Protein Name

 D-tagatose-1,6-bisphosphate aldolase subunit GatZ

Protein Synonyms/Alias

 

Gene Name

 gatZ

Gene Synonyms/Alias

 b2095, JW2082

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
 Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M
 Mol. Cell Proteomics 2008, Feb;7(2):299-307. [PMID:17938405]
 [2]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; Directproteinsequencing; Galactitolmetabolism; Referenceproteome

Protein Sequence

  GO:0003824   F:catalytic activity IEA:InterPro
  GO:2001059   P:D-tagatose 6-phosphate catabolic process IEA:UniProtKB-UniPathway
  GO:0019402   P:galactitol metabolic process IEA:UniProtKB-KW

  IPR013785   Aldolase_TIM.
  IPR023436   TagBP_ald_GatZ.
  IPR012062   TagBP_ald_GatZ/KbaZ.

  PF08013   Tagatose_6_P_K.