UniProt Accession

 LUXU_VIBHA;  P0C5S4;  Q9ZBB6

Genbank Protein ID

 L26221

Genbank Nucleotide ID

 AAD12737.2

Protein Name

 Phosphorelay protein LuxU

Protein Synonyms/Alias

 

Gene Name

 luxU

Gene Synonyms/Alias

 

Created Date

 3-June-2014

Organism

 Vibrio harveyi (Beneckea harveyi)

NCBI Taxa ID

 669

Phosphorylation

Reference

 [1]Sequence and function of LuxU: a two-component phosphorelay protein that regulates quorum sensing in Vibrio harveyi.
 Freeman JA,Bassler BL
 J. Bacteriol. 1999, Feb;181(3):899-906. [PMID:9922254]

Functional Description From UniProt

 FUNCTION: Phosphorelay protein which receives sensory signals from LuxN and LuxP and transmits them to LuxO, at low cell density LuxN and LuxP transfer a phosphoryl group to LuxU on His-58 and this phosphoryl group is further transferred to LuxO. At high cell density, as LuxU could function to establish an equilibrium between the aspartyl-phosphate of LuxN and the aspartyl-phosphate of LuxO, LuxU transfers phosphate from LuxO to LuxN (and probably LuxP) and finally phosphate is drained from the system

Sequence Annotation From UniProt

 MOD_RES 58 58 Phosphohistidine

Key Word From UniProt

 3D-structure; Phosphoprotein; Two-componentregulatorysystem.

Protein Sequence

  GO:0004871   F:signal transducer activity IEA:InterPro
  GO:0000160   P:phosphorelay signal transduction system IEA:UniProtKB-KW

  IPR008207   Sig_transdc_His_kin_Hpt_dom.

  PF01627   Hpt.

  SM00073   HPT.

  PS50894   HPT.