UniProt Accession

 SECB_ECOLI;  P0AG86;  P15040;  Q2M7S3

Genbank Protein ID

 M24489;  U00039;  U00096;  AP009048

Genbank Nucleotide ID

 AAA83907.1;  AAB18586.1;  AAC76633.1;  BAE77683.1

Protein Name

 Protein-export protein SecB

Protein Synonyms/Alias

 

Gene Name

 secB

Gene Synonyms/Alias

 b3609, JW3584

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
 Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M
 Mol. Cell Proteomics 2008, Feb;7(2):299-307. [PMID:17938405]
 [2]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]

Functional Description From UniProt

 FUNCTION: One of the proteins required for the normal export of some preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. Its substrates include AmpC, DegP, FhuA, FkpA, GBP, LamB, MalE (MBP), OmpA, OmpF, OmpT, OmpX, OppA, PhoE, TolB, TolC, YbgF, YcgK, YgiW and YncE

Sequence Annotation From UniProt

 

Key Word From UniProt

 3D-structure; Chaperone; Completeproteome; Cytoplasm; Proteintransport; Referenceproteome; Translocation; Transport

Protein Sequence

  GO:0005829   C:cytosol IDA:EcoCyc
  GO:0051082   F:unfolded protein binding IDA:EcoCyc
  GO:0006457   P:protein folding IEA:UniProtKB-HAMAP
  GO:0006605   P:protein targeting IMP:EcoliWiki
  GO:0051262   P:protein tetramerization IDA:EcoCyc
  GO:0015031   P:protein transport IMP:EcoliWiki
  GO:0043952   P:protein transport by the Sec complex IMP:EcoliWiki

  IPR003708   SecB.

  PF02556   SecB.

  PR01594   SECBCHAPRONE.