※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NADH-quinone oxidoreductase subunit B
Protein Synonyms/Alias
 
Gene Name
 nuoB
Gene Synonyms/Alias
 Z3546, ECs3171
Created Date
 3-June-2014
Organism
 Escherichia coli O157:H7
NCBI Taxa ID
 83334
Phosphorylation
Position
Peptide
Code
Type
References
193 VVGDQGVYRANMQSE Y HTP [1]
Reference
 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]
Functional Description From UniProt
 FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 4Fe-4S; Cellinnermembrane; Cellmembrane; Completeproteome; Iron; Iron-sulfur; Membrane; Metal-binding; NAD; Oxidoreductase; Quinone; Transport; Ubiquinone
Protein Sequence
 MDYTLTRIDP NGENDRYPLQ KQEIVTDPLE QEVNKNVFMG KLNDMVNWGR KNSIWPYNFG 60
 LSCCYVEMVT SFTAVHDVAR FGAEVLRASP RQADLMVVAG TCFTKMAPVI QRLYDQMLEP 120
 KWVISMGACA NSGGMYDIYS VVQGVDKFIP VDVYIPGCPP RPEAYMQALM LLQESIGKER 180
 RPLSWVVGDQ GVYRANMQSE RERKRGERIA VTNLRTPDEI 220
  GO:0005886   C:plasma membrane IEA:UniProtKB-SubCell
  GO:0051539   F:4 iron, 4 sulfur cluster binding IEA:UniProtKB-KW
  GO:0005506   F:iron ion binding IEA:UniProtKB-HAMAP
  GO:0008137   F:NADH dehydrogenase (ubiquinone) activity IEA:InterPro
  GO:0048038   F:quinone binding IEA:UniProtKB-KW
  GO:0006810   P:transport IEA:UniProtKB-KW
  IPR006137   NADH_UbQ_OxRdtase-like_20kDa.
  IPR006138   NADH_UQ_OxRdtase_20Kd_su.
  PF01058   Oxidored_q6.
  PS01150   COMPLEX1_20K.