※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nitrogen regulation protein NR(II)
Protein Synonyms/Alias
 
Gene Name
 glnL
Gene Synonyms/Alias
 glnR, ntrB; OrderedLocusNames=b3869, JW3840
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
139 DLVRGLAHEIKNPLG H LTP [1],UniProt
Reference
 [1]Identification of the site of autophosphorylation of the bacterial protein kinase/phosphatase NRII.
 Ninfa AJ,Bennett RL
 J. Biol. Chem. 1991, Apr, 15;266(11):6888-93. [PMID:2016302]
Functional Description From UniProt
 FUNCTION: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of NtrC. In nitrogen limitation NtrB activates NtrC by phosphorylating it, while in nitrogen excess NtrC is dephosphorylated and consequently inactivated by NtrB
Sequence Annotation From UniProt
 MOD_RES 139 139 Phosphohistidine; by autocatalysis
Key Word From UniProt
 3D-structure; ATP-binding; Completeproteome; Kinase; Nitrogenfixation; Nucleotide-binding; Phosphoprotein; Referenceproteome; Transferase; Two-componentregulatorysystem
Protein Sequence
 MATGTQPDAG QILNSLINSI LLIDDNLAIH YANPAAQQLL AQSSRKLFGT PLPELLSYFS 60
 LNIELMQESL EAGQGFTDNE VTLVIDGRSH ILSVTAQRMP DGMILLEMAP MDNQRRLSQE 120
 QLQHAQQVAA RDLVRGLAHE IKNPLGGLRG AAQLLSKALP DPSLLEYTKV IIEQADRLRN 180
 LVDRLLGPQL PGTRVTESIH KVAERVVTLV SMELPDNVRL IRDYDPSLPE LAHDPDQIEQ 240
 VLLNIVRNAL QALGPEGGEI ILRTRTAFQL TLHGERYRLA ARIDVEDNGP GIPPHLQDTL 300
 FYPMVSGREG GTGLGLSIAR NLIDQHSGKI EFTSWPGHTE FSVYLPIRK 349
  GO:0005622   C:intracellular IDA:EcoCyc
  GO:0016020   C:membrane IEA:InterPro
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0042802   F:identical protein binding IPI:IntAct
  GO:0004721   F:phosphoprotein phosphatase activity IDA:EcoCyc
  GO:0000155   F:phosphorelay sensor kinase activity IDA:EcoCyc
  GO:0016311   P:dephosphorylation IDA:GOC
  GO:0009399   P:nitrogen fixation IEA:UniProtKB-KW
  GO:0000160   P:phosphorelay signal transduction system IDA:EcoCyc
  GO:0046777   P:protein autophosphorylation IMP:EcoCyc
  GO:0051171   P:regulation of nitrogen compound metabolic process IMP:EcoCyc
  GO:0006355   P:regulation of transcription, DNA-templated IEA:InterPro
  GO:0023014   P:signal transduction by phosphorylation IDA:GOC
  IPR003661   EnvZ-like_dim/P.
  IPR003594   HATPase_ATP-bd.
  IPR000014   PAS.
  IPR013767   PAS_fold.
  IPR004358   Sig_transdc_His_kin-like_C.
  IPR005467   Sig_transdc_His_kinase_core.
  IPR009082   Sig_transdc_His_kinase_dimeric.
  PF02518   HATPase_c.
  PF00512   HisKA.
  PF00989   PAS.
  SM00387   HATPase_c.
  SM00388   HisKA.
  SM00091   PAS.
  PS50109   HIS_KIN.
  PS50112   PAS.
  PR00344   BCTRLSENSOR.