UniProt Accession

 RIDA_ECOLI;  P0AF93;  P39330;  P76806;  Q2M664

Genbank Protein ID

 U14003;  U00096;  AP009048

Genbank Nucleotide ID

 AAA97140.1;  AAC77200.2;  BAE78242.1

Protein Name

 2-iminobutanoate/2-iminopropanoate deaminase

Protein Synonyms/Alias

 

Gene Name

 ridA

Gene Synonyms/Alias

 yjgF; OrderedLocusNames=b4243, JW5755

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 3D-structure; Amino-acidbiosynthesis; Branched-chainaminoacidbiosynthesis; Completeproteome; Cytoplasm; Detoxification; Directproteinsequencing; Hydrolase; Isoleucinebiosynthesis; Referenceproteome

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0016020   C:membrane IDA:UniProtKB
  GO:0019239   F:deaminase activity ISS:UniProtKB
  GO:0016787   F:hydrolase activity IEA:UniProtKB-KW
  GO:0009097   P:isoleucine biosynthetic process IEA:UniProtKB-KW
  GO:0009636   P:response to toxic substance IEA:UniProtKB-KW

  IPR013813   Endoribo_LPSP/chorism_mut-like.
  IPR006056   YjgF-like.
  IPR019897   YjgF-like_CS.
  IPR006175   YjgF/Yer057p/UK114.

  PF01042   Ribonuc_L-PSP.

  PS01094   UPF0076.