※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Protein Synonyms/Alias
 ENR
Gene Name
 fabI
Gene Synonyms/Alias
 Z2512, ECs1861
Created Date
 3-June-2014
Organism
 Escherichia coli O157:H7
NCBI Taxa ID
 83334
Phosphorylation
Position
Peptide
Code
Type
References
156 AERAIPNYNVMGLAK Y HTP [1]
Reference
 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]
Functional Description From UniProt
 FUNCTION: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Antibioticresistance; Biotinbiosynthesis; Completeproteome; Fattyacidbiosynthesis; Fattyacidmetabolism; Lipidbiosynthesis; Lipidmetabolism; NAD; Oxidoreductase
Protein Sequence
 MGFLSGKRIL VTGVASKLSI AYGIAQAMHR EGAELAFTYQ NDKLKGRVEE FAAQLGSDIV 60
 LQCDVAEDAS IDTMFAELGK VWPKFDGFVH SIGFAPGDQL DGDYVNAVTR EGFKIAHDIS 120
 SYSFVAMAKA CRSMLNPGSA LLTLSYLGAE RAIPNYNVMG LAKASLEANV RYMANAMGPE 180
 GVRVNAISAG PIRTLAASGI KDFRKMLAHC EAVTPIRRTV TIEDVGNSAA FLCSDLSAGI 240
 SGEVVHVDGG FSIAAMNELE LK 262
  GO:0004318   F:enoyl-[acyl-carrier-protein] reductase (NADH) activity ISS:UniProtKB
  GO:0009102   P:biotin biosynthetic process ISS:UniProtKB
  GO:0030497   P:fatty acid elongation ISS:UniProtKB
  GO:0051289   P:protein homotetramerization ISS:UniProtKB
  GO:0046677   P:response to antibiotic IEA:UniProtKB-KW
  IPR014358   Enoyl-ACP_Rdtase_NADH.
  IPR002347   Glc/ribitol_DH.
  IPR016040   NAD(P)-bd_dom.
  PR00081   GDHRDH.