UniProt Accession

 FABG_ECOLI;  P0AEK2;  P25716;  P78221;  Q47202

Genbank Protein ID

 M84991;  U00096;  AP009048;  M87040

Genbank Nucleotide ID

 AAA23739.1;  AAC74177.1;  BAA35901.1;  AAA23743.1

Protein Name

 3-oxoacyl-[acyl-carrier-protein] reductase FabG

Protein Synonyms/Alias

 

Gene Name

 fabG

Gene Synonyms/Alias

 b1093, JW1079

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]

Functional Description From UniProt

 FUNCTION: Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis

Sequence Annotation From UniProt

 

Key Word From UniProt

 3D-structure; Calcium; Completeproteome; Fattyacidbiosynthesis; Fattyacidmetabolism; Lipidbiosynthesis; Lipidmetabolism; Metal-binding; NADP; Oxidoreductase; Referenceproteome

Protein Sequence

  GO:0004316   F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity IMP:UniProtKB
  GO:0042802   F:identical protein binding IDA:EcoCyc
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  GO:0051287   F:NAD binding IEA:InterPro
  GO:0050661   F:NADP binding IDA:UniProtKB
  GO:0009102   P:biotin biosynthetic process IMP:EcoCyc
  GO:0006633   P:fatty acid biosynthetic process IMP:EcoCyc
  GO:0030497   P:fatty acid elongation IMP:UniProtKB
  GO:0008610   P:lipid biosynthetic process IMP:EcoCyc

  IPR011284   3oxo_ACP_reduc.
  IPR002198   DH_sc/Rdtase_SDR.
  IPR002347   Glc/ribitol_DH.
  IPR016040   NAD(P)-bd_dom.
  IPR020904   Sc_DH/Rdtase_CS.

  PF00106   adh_short.

  PS00061   ADH_SHORT.

  PR00081   GDHRDH.
  PR00080   SDRFAMILY.