※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Response regulator UvrY
Protein Synonyms/Alias
 
Gene Name
 uvrY
Gene Synonyms/Alias
 yecB; OrderedLocusNames=b1914, JW1899
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
101 MQAGAAGYLSKGAAP Y HTP [1]
119 VSAIRSVYSGQRYIA Y HTP [1]
Reference
 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]
Functional Description From UniProt
 FUNCTION: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop Mediates the effects of CsrA on csrB RNA by BarA-dependent and BarA-independent mechanisms
Sequence Annotation From UniProt
 MOD_RES 54 54 4-aspartylphosphate (By similarity)
Key Word From UniProt
 Completeproteome; Cytoplasm; DNA-binding; Phosphoprotein; Referenceproteome; Transcription; Transcriptionregulation; Two-componentregulatorysystem
Protein Sequence
 MINVLLVDDH ELVRAGIRRI LEDIKGIKVV GEASCGEDAV KWCRTNAVDV VLMDMSMPGI 60
 GGLEATRKIA RSTADVKIIM LTVHTENPLP AKVMQAGAAG YLSKGAAPQE VVSAIRSVYS 120
 GQRYIASDIA QQMALSQIEP EKTESPFASL SERELQIMLM ITKGQKVNEI SEQLNLSPKT 180
 VNSYRYRMFS KLNIHGDVEL THLAIRHGLC NAETLSSQ 218
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0003677   F:DNA binding IEA:UniProtKB-KW
  GO:0000156   F:phosphorelay response regulator activity IDA:EcoCyc
  GO:0003700   F:sequence-specific DNA binding transcription factor activity IEA:InterPro
  GO:0035556   P:intracellular signal transduction IDA:GOC
  GO:0000160   P:phosphorelay signal transduction system IDA:EcoCyc
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR011006   CheY-like_superfamily.
  IPR016032   Sig_transdc_resp-reg_C-effctor.
  IPR001789   Sig_transdc_resp-reg_receiver.
  IPR000792   Tscrpt_reg_LuxR_C.
  IPR011991   WHTH_DNA-bd_dom.
  PF00196   GerE.
  PF00072   Response_reg.
  SM00421   HTH_LUXR.
  SM00448   REC.
  PS00622   HTH_LUXR_1.
  PS50043   HTH_LUXR_2.
  PS50110   RESPONSE_REGULATORY.
  PR00038   HTHLUXR.