UniProt Accession

 MAP1_ECO57;  P0AE20;  P07906

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG54470.1;  BAB33593.1

Protein Name

 Methionine aminopeptidase

Protein Synonyms/Alias

 MAP;  MetAP

Gene Name

 map

Gene Synonyms/Alias

 Z0178, ECs0170

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Removes the N-terminal methionine from nascent proteins The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Aminopeptidase; Completeproteome; Hydrolase; Metal-binding; Protease.

Protein Sequence

  GO:0046872   F:metal ion binding IEA:UniProtKB-HAMAP
  GO:0070006   F:metalloaminopeptidase activity IEA:UniProtKB-HAMAP
  GO:0070084   P:protein initiator methionine removal IEA:UniProtKB-HAMAP

  IPR001714   Pept_M24_MAP.
  IPR000994   Pept_M24_structural-domain.
  IPR002467   Pept_M24A_MAP1.

  PF00557   Peptidase_M24.

  PS00680   MAP_1.

  PR00599   MAPEPTIDASE.