※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lipoprotein-releasing system transmembrane protein LolC
Protein Synonyms/Alias
 
Gene Name
 lolC
Gene Synonyms/Alias
 Z1757, ECs1494
Created Date
 3-June-2014
Organism
 Escherichia coli O157:H7
NCBI Taxa ID
 83334
Phosphorylation
Position
Peptide
Code
Type
References
398 QPAEALRYE****** Y HTP [1]
Reference
 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]
Functional Description From UniProt
 FUNCTION: Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity)
Sequence Annotation From UniProt
 TRANSMEM 25 45 Helical; (Potential)
 TRANSMEM 270 290 Helical; (Potential)
 TRANSMEM 310 330 Helical; (Potential)
 TRANSMEM 358 378 Helical; (Potential)
Key Word From UniProt
 Cellinnermembrane; Cellmembrane; Completeproteome; Membrane; Transmembrane; Transmembranehelix; Transport
Protein Sequence
 MYQPVALFIG LRYMRGRAAD RFGRFVSWLS TIGITLGVMA LVTVLSVMNG FERELQNNIL 60
 GLMPQAILSS EHGSLNPQQL PETAVKLDGV NRVAPITTGD VVLQSARSVA VGVMLGIDPA 120
 QKDPLTPYLV NVKQTDLEPG KYNVILGEQL ASQLGVNRGD QIRVMVPSAS QFTPMGRIPS 180
 QRLFNVIGTF AANSEVDGYE MLVNIEDASR LMRYPAGNIT GWRLWLDEPL KVDSLSQQKL 240
 PEGSKWQDWR DRKGELFQAV RMEKNMMGLL LSLIVAVAAF NIITSLGLMV MEKQGEVAIL 300
 QTQGLTPRQI MMVFMVQGAS AGIIGAILGA ALGALLASQL NNLMPIIGVL LDGAALPVAI 360
 EPLQVIVIAL VAMAIALLST LYPSWRAAAT QPAEALRYE 399
  GO:0016021   C:integral component of membrane IEA:UniProtKB-KW
  GO:0005886   C:plasma membrane IEA:UniProtKB-SubCell
  GO:0042954   F:lipoprotein transporter activity IEA:InterPro
  IPR011925   LolCE_TM.
  IPR025857   MacB_PCD.
  IPR003838   Permease_FtsX-like.
  PF02687   FtsX.
  PF12704   MacB_PCD.