UniProt Accession

 HHA_ECO57;  P0ACE5;  P23870;  P77120

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG54809.1;  BAB33936.1

Protein Name

 Hemolysin expression-modulating protein Hha

Protein Synonyms/Alias

 

Gene Name

 hha

Gene Synonyms/Alias

 Z0573, ECs0513

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Down-regulates hemolysin expression, in complex with H- NS, and can also stimulate transposition events in vivo. Binds DNA and influences DNA topology in response to environmental stimuli Decreases biofilm formation (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; DNA-binding; Repressor; Transcription; Transcriptionregulation

Protein Sequence

  GO:0003677   F:DNA binding IEA:UniProtKB-KW
  GO:1900191   P:negative regulation of single-species biofilm formation IMP:CACAO
  GO:0006355   P:regulation of transcription, DNA-templated IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW

  IPR007985   Hemolysn_expr_modulating_HHA.

  PF05321   HHA.