UniProt Accession

 ISCU_ECO57;  P0ACD6;  P77310

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG57643.1;  BAB36818.1

Protein Name

 Iron-sulfur cluster assembly scaffold protein IscU

Protein Synonyms/Alias

 

Gene Name

 iscU

Gene Synonyms/Alias

 nifU; OrderedLocusNames=Z3796, ECs3395

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: A scaffold on which IscS assembles Fe-S clusters Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (Probable)

Sequence Annotation From UniProt

 

Key Word From UniProt

 3D-structure; Completeproteome.

Protein Sequence

  GO:0005506   F:iron ion binding IEA:InterPro
  GO:0051536   F:iron-sulfur cluster binding IEA:InterPro
  GO:0016226   P:iron-sulfur cluster assembly IEA:InterPro

  IPR011339   ISC_FeS_clus_asmbl_IscU.
  IPR002871   NIF_FeS_clus_asmbl_NifU_N.

  PF01592   NifU_N.