UniProt Accession

 SSPA_ECOLI;  P0ACA3;  P05838;  Q2M8Y4

Genbank Protein ID

 X05088;  U18997;  U00096;  AP009048

Genbank Nucleotide ID

 CAA28740.1;  AAA58031.1;  AAC76261.1;  BAE77272.1

Protein Name

 Stringent starvation protein A

Protein Synonyms/Alias

 

Gene Name

 sspA

Gene Synonyms/Alias

 pog, ssp; OrderedLocusNames=b3229, JW3198

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]

Functional Description From UniProt

 FUNCTION: Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme. It is synthesized predominantly when cells are exposed to amino acid starvation, at which time it accounts for over 50% of the total protein synthesized. It is involved in the transition from P1 early to P1 late gene expression. Rnk and SspA can functionally replace P.aeruginosa alginate regulatory gene algR2

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; Directproteinsequencing; Referenceproteome; Stressresponse

Protein Sequence

  GO:0045893   P:positive regulation of transcription, DNA-templated IDA:EcoCyc
  GO:0042594   P:response to starvation IEP:EcoCyc

  IPR010987   Glutathione-S-Trfase_C-like.
  IPR004045   Glutathione_S-Trfase_N.
  IPR004046   GST_C.
  IPR012336   Thioredoxin-like_fold.

  PF00043   GST_C.
  PF02798   GST_N.

  PS50405   GST_CTER.
  PS50404   GST_NTER.