UniProt Accession

 GLRX4_ECOLI;  P0AC69;  P37010;  P77424

Genbank Protein ID

 U00096;  AP009048;  L01622

Genbank Nucleotide ID

 AAC74726.1;  BAA15420.1;  AAC37010.1

Protein Name

 Glutaredoxin-4

Protein Synonyms/Alias

 Grx4

Gene Name

 grxD

Gene Synonyms/Alias

 ydhD; OrderedLocusNames=b1654, JW1646

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (Probable)

Sequence Annotation From UniProt

 

Key Word From UniProt

 2Fe-2S; 3D-structure; Completeproteome; Cytoplasm; Iron; Iron-sulfur; Metal-binding; Redox-activecenter; Referenceproteome

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0051537   F:2 iron, 2 sulfur cluster binding IDA:EcoCyc
  GO:0009055   F:electron carrier activity IEA:InterPro
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  GO:0015035   F:protein disulfide oxidoreductase activity IEA:InterPro
  GO:0045454   P:cell redox homeostasis IEA:InterPro

  IPR002109   Glutaredoxin.
  IPR014434   Monothiol_GRX.
  IPR004480   Monothiol_GRX-rel.
  IPR012336   Thioredoxin-like_fold.

  PF00462   Glutaredoxin.

  PS51354   GLUTAREDOXIN_2.