※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutaredoxin-3
Protein Synonyms/Alias
 Grx3
Gene Name
 grxC
Gene Synonyms/Alias
 yibM; OrderedLocusNames=b3610, JW3585
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
28 LLSSKGVSFQELPID S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfide bonds in a coupled system with glutathione reductase
Sequence Annotation From UniProt
 DISULFID 12 15 Redox-active (By similarity)
Key Word From UniProt
 3D-structure; Completeproteome; Deoxyribonucleotidesynthesis; Directproteinsequencing; Disulfidebond; Electrontransport; Redox-activecenter; Referenceproteome; Transport
Protein Sequence
 MANVEIYTKE TCPYCHRAKA LLSSKGVSFQ ELPIDGNAAK REEMIKRSGR TTVPQIFIDA 60
 QHIGGCDDLY ALDARGGLDP LLK 83
  GO:0009055   F:electron carrier activity IEA:InterPro
  GO:0043295   F:glutathione binding IDA:EcoCyc
  GO:0015035   F:protein disulfide oxidoreductase activity IDA:EcoCyc
  GO:0045454   P:cell redox homeostasis IEA:InterPro
  GO:0009263   P:deoxyribonucleotide biosynthetic process IEA:UniProtKB-KW
  IPR011767   GLR_AS.
  IPR002109   Glutaredoxin.
  IPR014025   Glutaredoxin_subgr.
  IPR011900   GRX_bact.
  IPR012336   Thioredoxin-like_fold.
  PF00462   Glutaredoxin.
  PS00195   GLUTAREDOXIN_1.
  PS51354   GLUTAREDOXIN_2.
  PR00160   GLUTAREDOXIN.