UniProt Accession

 GLRX2_ECOLI;  P0AC59;  P39811;  P75928;  P77043

Genbank Protein ID

 X92076;  U00096;  AP009048

Genbank Nucleotide ID

 CAA63058.1;  AAC74148.1;  BAA35872.1

Protein Name

 Glutaredoxin-2

Protein Synonyms/Alias

 Grx2

Gene Name

 grxB

Gene Synonyms/Alias

 b1064, JW1051

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
 [2]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Involved in reducing some disulfide bonds in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase

Sequence Annotation From UniProt

 DISULFID 9 12 Redox-active (By similarity)

Key Word From UniProt

 3D-structure; Completeproteome; Directproteinsequencing; Disulfidebond; Electrontransport; Redox-activecenter; Referenceproteome; Transport

Protein Sequence

  GO:0005829   C:cytosol IDA:EcoCyc
  GO:0009055   F:electron carrier activity IEA:InterPro
  GO:0015038   F:glutathione disulfide oxidoreductase activity IDA:EcoCyc
  GO:0015035   F:protein disulfide oxidoreductase activity IEA:InterPro
  GO:0045454   P:cell redox homeostasis IEA:InterPro

  IPR011767   GLR_AS.
  IPR007494   Glutaredoxin2_C.
  IPR010987   Glutathione-S-Trfase_C-like.
  IPR004045   Glutathione_S-Trfase_N.
  IPR011901   GRXB.
  IPR012336   Thioredoxin-like_fold.

  PF04399   Glutaredoxin2_C.
  PF13417   GST_N_3.

  PS00195   GLUTAREDOXIN_1.
  PS50404   GST_NTER.