UniProt Accession

 CYOA_ECOLI;  P0ABJ1;  P18400;  Q2MBZ4

Genbank Protein ID

 J05492;  U82664;  U00096;  AP009048;  M55258;  S67816

Genbank Nucleotide ID

 AAA23631.1;  AAB40188.1;  AAC73535.1;  BAE76212.1;  AAA23630.1;  AAB28885.1

Protein Name

 Cytochrome bo(3) ubiquinol oxidase subunit 2

Protein Synonyms/Alias

 Cytochrome o subunit 2

Gene Name

 cyoA

Gene Synonyms/Alias

 b0432, JW0422

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron

Sequence Annotation From UniProt

 TRANSMEM 51 68 Helical; (Probable)
 TRANSMEM 93 111 Helical; (Probable)

Key Word From UniProt

 3D-structure; Cellinnermembrane; Cellmembrane; Completeproteome; Directproteinsequencing; Electrontransport; Lipoprotein; Membrane; Oxidoreductase; Palmitate; Referenceproteome; Respiratorychain; Signal; Transmembrane; Transmembranehelix; Transport

Protein Sequence

  GO:0009319   C:cytochrome o ubiquinol oxidase complex IDA:EcoCyc
  GO:0005887   C:integral component of plasma membrane IDA:EcoliWiki
  GO:0070469   C:respiratory chain IEA:UniProtKB-KW
  GO:0005507   F:copper ion binding IEA:InterPro
  GO:0009486   F:cytochrome bo3 ubiquinol oxidase activity IEA:InterPro
  GO:0008827   F:cytochrome o ubiquinol oxidase activity IEA:InterPro
  GO:0004129   F:cytochrome-c oxidase activity IEA:InterPro
  GO:0009055   F:electron carrier activity IDA:EcoCyc
  GO:0015078   F:hydrogen ion transmembrane transporter activity IDA:EcoCyc
  GO:0015453   F:oxidoreduction-driven active transmembrane transporter activity IDA:EcoCyc
  GO:0048039   F:ubiquinone binding IDA:EcoCyc
  GO:0019646   P:aerobic electron transport chain IMP:EcoCyc
  GO:1902600   P:hydrogen ion transmembrane transport IDA:GOC
  GO:0055085   P:transmembrane transport IDA:GOC

  IPR012141   Bo-type_Ubol_Oxase_su_II.
  IPR010514   COX_ARM.
  IPR008972   Cupredoxin.
  IPR002429   Cyt_c_oxidase_su2_C.
  IPR011759   Cyt_c_oxidase_su2_TM_dom.
  IPR006333   Cyt_o_ubiquinol_oxidase_su2.

  PF00116   COX2.
  PF06481   COX_ARM.

  PS50857   COX2_CUA.
  PS50999   COX2_TM.
  PS51257   PROKAR_LIPOPROTEIN.