UniProt Accession

 IRAP_ECO57;  P0AAP0;  P21831;  P77383

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG54728.1;  BAB33855.1

Protein Name

 Anti-adapter protein IraP

Protein Synonyms/Alias

 

Gene Name

 iraP

Gene Synonyms/Alias

 Z0478, ECs0432

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (By similarity)

Sequence Annotation From UniProt

 COILED 1 36 Potential

Key Word From UniProt

 Coiledcoil; Completeproteome; Cytoplasm; Stressresponse.

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0006950   P:response to stress IEA:UniProtKB-KW

  IPR019732   SigmaS_Anti-adapt_IraP.

  PF10796   Anti-adapt_IraP.