UniProt Accession

 OMPR_ECO57;  P0AA18;  O31133;  P03025;  P08981;  P41405

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG58506.1;  BAB37670.1

Protein Name

 Transcriptional regulatory protein OmpR

Protein Synonyms/Alias

 

Gene Name

 ompR

Gene Synonyms/Alias

 Z4760, ECs4247

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the OmpR protein. As a multimer, it turns on the expression of the ompC gene; as a monomer, it turns on the expression of the ompF gene (By similarity)

Sequence Annotation From UniProt

 MOD_RES 55 55 4-aspartylphosphate (By similarity)

Key Word From UniProt

 Activator; Completeproteome; Cytoplasm; DNA-binding; Phosphoprotein; Repressor; Transcription; Transcriptionregulation; Two-componentregulatorysystem

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0003677   F:DNA binding IEA:UniProtKB-KW
  GO:0000156   F:phosphorelay response regulator activity IEA:InterPro
  GO:0006355   P:regulation of transcription, DNA-templated IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW

  IPR011006   CheY-like_superfamily.
  IPR001867   Sig_transdc_resp-reg_C.
  IPR016032   Sig_transdc_resp-reg_C-effctor.
  IPR001789   Sig_transdc_resp-reg_receiver.
  IPR011991   WHTH_DNA-bd_dom.

  PF00072   Response_reg.
  PF00486   Trans_reg_C.

  SM00448   REC.
  SM00862   Trans_reg_C.

  PS50110   RESPONSE_REGULATORY.