※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional regulatory protein OmpR
Protein Synonyms/Alias
 
Gene Name
 ompR
Gene Synonyms/Alias
 kmt, ompB; OrderedLocusNames=b3405, JW3368
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
55 SFHLMVLDLMLPGED D LTP [1],UniProt
Reference
 [1]Identification of a phosphorylation site and functional analysis of conserved aspartic acid residues of OmpR, a transcriptional activator for ompF and ompC in Escherichia coli.
 Delgado J,Forst S,Harlocker S,Inouye M
 Mol. Microbiol. 1993, Dec;10(5):1037-47. [PMID:7934854]
Functional Description From UniProt
 FUNCTION: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the OmpR protein. As a multimer, it turns on the expression of the ompC gene; as a monomer, it turns on the expression of the ompF gene
Sequence Annotation From UniProt
 MOD_RES 55 55 4-aspartylphosphate
Key Word From UniProt
 3D-structure; Activator; Completeproteome; Cytoplasm; DNA-binding; Phosphoprotein; Referenceproteome; Repressor; Transcription; Transcriptionregulation; Two-componentregulatorysystem
Protein Sequence
 MQENYKILVV DDDMRLRALL ERYLTEQGFQ VRSVANAEQM DRLLTRESFH LMVLDLMLPG 60
 EDGLSICRRL RSQSNPMPII MVTAKGEEVD RIVGLEIGAD DYIPKPFNPR ELLARIRAVL 120
 RRQANELPGA PSQEEAVIAF GKFKLNLGTR EMFREDEPMP LTSGEFAVLK ALVSHPREPL 180
 SRDKLMNLAR GREYSAMERS IDVQISRLRR MVEEDPAHPR YIQTVWGLGY VFVPDGSKA 239
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0003677   F:DNA binding IEA:UniProtKB-KW
  GO:0000156   F:phosphorelay response regulator activity IDA:EcoliWiki
  GO:0035556   P:intracellular signal transduction IDA:GOC
  GO:0000160   P:phosphorelay signal transduction system IDA:EcoliWiki
  GO:0045893   P:positive regulation of transcription, DNA-templated IDA:EcoliWiki
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR011006   CheY-like_superfamily.
  IPR001867   Sig_transdc_resp-reg_C.
  IPR016032   Sig_transdc_resp-reg_C-effctor.
  IPR001789   Sig_transdc_resp-reg_receiver.
  IPR011991   WHTH_DNA-bd_dom.
  PF00072   Response_reg.
  PF00486   Trans_reg_C.
  SM00448   REC.
  SM00862   Trans_reg_C.
  PS50110   RESPONSE_REGULATORY.