※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HTH-type transcriptional regulator CysB
Protein Synonyms/Alias
 
Gene Name
 cysB
Gene Synonyms/Alias
 Z2535, ECs1847
Created Date
 3-June-2014
Organism
 Escherichia coli O157:H7
NCBI Taxa ID
 83334
Phosphorylation
Position
Peptide
Code
Type
References
27 SSTAEGLYTSQPGIS Y HTP [1]
Reference
 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]
Functional Description From UniProt
 FUNCTION: This protein is a positive regulator of gene expression for the cysteine regulon. The inducer for CysB is N-acetylserine (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Activator; Amino-acidbiosynthesis; Completeproteome; Cysteinebiosynthesis; Cytoplasm; DNA-binding; Transcription; Transcriptionregulation
Protein Sequence
 MKLQQLRYIV EVVNHNLNVS STAEGLYTSQ PGISKQVRML EDELGIQIFS RSGKHLTQVT 60
 PAGQEIIRIA REVLSKVDAI KSVAGEHTWP DKGSLYIATT HTQARYALPN VIKGFIERYP 120
 RVSLHMHQGS PTQIADAVSK GNADFAIATE ALHLYEDLVM LPCYHWNRAI VVTPDHPLAG 180
 KKAITIEELA QYPLVTYTFG FTGRSELDTA FNRAGLTPRI VFTATDADVI KTYVRLGLGV 240
 GVIASMAVDP VADPDLVRVD AHDIFSHSTT KIGFRRSTFL RSYMYDFIQR FAPHLTRDVV 300
 DAAVALRSNE EIEVMFKDIK LPEK 324
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0003677   F:DNA binding IEA:UniProtKB-KW
  GO:0003700   F:sequence-specific DNA binding transcription factor activity IEA:InterPro
  GO:0019344   P:cysteine biosynthetic process IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR005119   LysR_subst-bd.
  IPR000847   Tscrpt_reg_HTH_LysR.
  IPR011991   WHTH_DNA-bd_dom.
  PF00126   HTH_1.
  PF03466   LysR_substrate.
  PS50931   HTH_LYSR.
  PR00039   HTHLYSR.