※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inorganic pyrophosphatase
Protein Synonyms/Alias
 PPase
Gene Name
 ppa
Gene Synonyms/Alias
 b4226, JW4185
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
142 IAHFFEHYKDLEKGK Y HTP [1]
2 ******MSLLNVPAG S HTP [2]
115 AVPHSKLSKEYDHIK S HTP [2]
112 KLVAVPHSKLSKEYD S HTP [2]
Reference
 [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
 Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M
 Mol. Cell Proteomics 2008, Feb;7(2):299-307. [PMID:17938405]
 [2]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; Completeproteome; Cytoplasm; Directproteinsequencing; Hydrolase; Magnesium; Metal-binding; Referenceproteome
Protein Sequence
 MSLLNVPAGK DLPEDIYVVI EIPANADPIK YEIDKESGAL FVDRFMSTAM FYPCNYGYIN 60
 HTLSLDGDPV DVLVPTPYPL QPGSVIRCRP VGVLKMTDEA GEDAKLVAVP HSKLSKEYDH 120
 IKDVNDLPEL LKAQIAHFFE HYKDLEKGKW VKVEGWENAE AAKAEIVASF ERAKNK 176
  GO:0005829   C:cytosol IDA:UniProtKB
  GO:0016020   C:membrane IDA:UniProtKB
  GO:0004427   F:inorganic diphosphatase activity IDA:EcoCyc
  GO:0000287   F:magnesium ion binding IDA:EcoCyc
  GO:0050355   F:triphosphatase activity IDA:EcoCyc
  GO:0008270   F:zinc ion binding IDA:EcoCyc
  GO:0006796   P:phosphate-containing compound metabolic process IEA:InterPro
  IPR008162   Pyrophosphatase.
  PF00719   Pyrophosphatase.
  PS00387   PPASE.