UniProt Accession

 NDK_ECO57;  P0A764;  P24233

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG57628.1;  BAB36803.1

Protein Name

 Nucleoside diphosphate kinase

Protein Synonyms/Alias

 NDK;  NDP kinase

Gene Name

 ndk

Gene Synonyms/Alias

 Z3781, ECs3380

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)

Sequence Annotation From UniProt

 MOD_RES 119 119 Phosphoserine (By similarity)
 MOD_RES 121 121 Phosphoserine (By similarity)

Key Word From UniProt

 ATP-binding; Completeproteome; Cytoplasm; Kinase; Magnesium; Metal-binding; Nucleotidemetabolism; Nucleotide-binding; Phosphoprotein; Transferase

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  GO:0004550   F:nucleoside diphosphate kinase activity IEA:UniProtKB-HAMAP
  GO:0006241   P:CTP biosynthetic process IEA:UniProtKB-HAMAP
  GO:0006183   P:GTP biosynthetic process IEA:UniProtKB-HAMAP
  GO:0006228   P:UTP biosynthetic process IEA:UniProtKB-HAMAP

  IPR001564   Nucleoside_diP_kinase.
  IPR023005   Nucleoside_diP_kinase_AS.

  PF00334   NDK.

  SM00562   NDK.

  PS00469   NDP_KINASES.

  PR01243   NUCDPKINASE.