UniProt Accession

 KPRS_ECO57;  P0A719;  P08330;  P76828;  P78058

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG56065.1;  BAB35135.1

Protein Name

 Ribose-phosphate pyrophosphokinase

Protein Synonyms/Alias

 RPPK;  P-Rib-PP synthase;  PRPP synthase

Gene Name

 prs

Gene Synonyms/Alias

 prsA; OrderedLocusNames=Z1978, ECs1712

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 

Sequence Annotation From UniProt

 

Key Word From UniProt

 ATP-binding; Completeproteome; Cytoplasm; Kinase; Magnesium; Metal-binding; Nucleotidebiosynthesis; Nucleotide-binding; Transferase

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0016301   F:kinase activity IEA:UniProtKB-KW
  GO:0000287   F:magnesium ion binding IEA:UniProtKB-HAMAP
  GO:0004749   F:ribose phosphate diphosphokinase activity IEA:UniProtKB-HAMAP
  GO:0006015   P:5-phosphoribose 1-diphosphate biosynthetic process IEA:UniProtKB-UniPathway
  GO:0009165   P:nucleotide biosynthetic process IEA:UniProtKB-KW
  GO:0009156   P:ribonucleoside monophosphate biosynthetic process IEA:UniProtKB-HAMAP

  IPR000842   PRib_PP_synth_CS.
  IPR005946   Rib-P_diPkinase.

  PF14572   Pribosyl_synth.

  PS00114   PRPP_SYNTHASE.