UniProt Accession

 IF3_ECO57;  P0A709;  P02999;  P76905

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG56705.1;  BAB35848.1

Protein Name

 Translation initiation factor IF-3

Protein Synonyms/Alias

 

Gene Name

 infC

Gene Synonyms/Alias

 Z2747, ECs2425

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; Cytoplasm; Initiationfactor; Proteinbiosynthesis.

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0003743   F:translation initiation factor activity IEA:UniProtKB-KW

  IPR019813   Translation_initiation_fac3_CS.
  IPR001288   Translation_initiation_fac_3.
  IPR019815   Translation_initiation_fac_3_C.
  IPR019814   Translation_initiation_fac_3_N.

  PF00707   IF3_C.
  PF05198   IF3_N.

  PS00938   IF3.