※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Translation initiation factor IF-3
Protein Synonyms/Alias
 
Gene Name
 infC
Gene Synonyms/Alias
 fit; OrderedLocusNames=b1718, JW5829
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
163 AVVESFPTKIEGRQM T HTP [1]
160 QELAVVESFPTKIEG S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Sequence Annotation From UniProt
 MOD_RES 1 1 N-methylmethionine; in Translation
Key Word From UniProt
 3D-structure; Cleavageonpairofbasicresidues; Completeproteome; Cytoplasm; Directproteinsequencing; Initiationfactor; Methylation; Phosphoprotein; Proteinbiosynthesis; Referenceproteome; RNA-binding
Protein Sequence
 MKGGKRVQTA RPNRINGEIR AQEVRLTGLE GEQLGIVSLR EALEKAEEAG VDLVEISPNA 60
 EPPVCRIMDY GKFLYEKSKS SKEQKKKQKV IQVKEIKFRP GTDEGDYQVK LRSLIRFLEE 120
 GDKAKITLRF RGREMAHQQI GMEVLNRVKD DLQELAVVES FPTKIEGRQM IMVLAPKKKQ 180
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0016020   C:membrane IDA:UniProtKB
  GO:0043022   F:ribosome binding IDA:EcoCyc
  GO:0003743   F:translation initiation factor activity IDA:EcoCyc
  GO:0009409   P:response to cold IDA:EcoCyc
  GO:0032790   P:ribosome disassembly IMP:EcoCyc
  IPR019813   Translation_initiation_fac3_CS.
  IPR001288   Translation_initiation_fac_3.
  IPR019815   Translation_initiation_fac_3_C.
  IPR019814   Translation_initiation_fac_3_N.
  PF00707   IF3_C.
  PF05198   IF3_N.
  PS00938   IF3.