※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Translation initiation factor IF-2
Protein Synonyms/Alias
 
Gene Name
 infB
Gene Synonyms/Alias
 ssyG; OrderedLocusNames=b3168, JW3137
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
293 KGGKRKGSSLQQGFQ S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Sequence Annotation From UniProt
 MOD_RES 808 808 N6-acetyllysine
Key Word From UniProt
 3D-structure; Acetylation; Alternativeinitiation; Completeproteome; Cytoplasm; Directproteinsequencing; GTP-binding; Initiationfactor; Nucleotide-binding; Proteinbiosynthesis; Referenceproteome
Protein Sequence
 MTDVTIKTLA AERQTSVERL VQQFADAGIR KSADDSVSAQ EKQTLIDHLN QKNSGPDKLT 60
 LQRKTRSTLN IPGTGGKSKS VQIEVRKKRT FVKRDPQEAE RLAAEEQAQR EAEEQARREA 120
 EESAKREAQQ KAEREAAEQA KREAAEQAKR EAAEKDKVSN QQDDMTKNAQ AEKARREQEA 180
 AELKRKAEEE ARRKLEEEAR RVAEEARRMA EENKWTDNAE PTEDSSDYHV TTSQHARQAE 240
 DESDREVEGG RGRGRNAKAA RPKKGNKHAE SKADREEARA AVRGGKGGKR KGSSLQQGFQ 300
 KPAQAVNRDV VIGETITVGE LANKMAVKGS QVIKAMMKLG AMATINQVID QETAQLVAEE 360
 MGHKVILRRE NELEEAVMSD RDTGAAAEPR APVVTIMGHV DHGKTSLLDY IRSTKVASGE 420
 AGGITQHIGA YHVETENGMI TFLDTPGHAA FTSMRARGAQ ATDIVVLVVA ADDGVMPQTI 480
 EAIQHAKAAQ VPVVVAVNKI DKPEADPDRV KNELSQYGIL PEEWGGESQF VHVSAKAGTG 540
 IDELLDAILL QAEVLELKAV RKGMASGAVI ESFLDKGRGP VATVLVREGT LHKGDIVLCG 600
 FEYGRVRAMR NELGQEVLEA GPSIPVEILG LSGVPAAGDE VTVVRDEKKA REVALYRQGK 660
 FREVKLARQQ KSKLENMFAN MTEGEVHEVN IVLKADVQGS VEAISDSLLK LSTDEVKVKI 720
 IGSGVGGITE TDATLAAASN AILVGFNVRA DASARKVIEA ESLDLRYYSV IYNLIDEVKA 780
 AMSGMLSPEL KQQIIGLAEV RDVFKSPKFG AIAGCMVTEG VVKRHNPIRV LRDNVVIYEG 840
 ELESLRRFKD DVNEVRNGME CGIGVKNYND VRTGDVIEVF EIIEIQRTIA 890
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0016020   C:membrane IDA:UniProtKB
  GO:0005525   F:GTP binding IEA:UniProtKB-KW
  GO:0003924   F:GTPase activity IDA:EcoCyc
  GO:0097216   F:guanosine tetraphosphate binding IDA:EcoCyc
  GO:0043024   F:ribosomal small subunit binding IDA:EcoCyc
  GO:0003743   F:translation initiation factor activity IDA:EcoCyc
  GO:0006184   P:GTP catabolic process IDA:GOC
  GO:0006413   P:translational initiation IDA:EcoCyc
  IPR009061   DNA-bd_dom_put.
  IPR000795   EF_GTP-bd_dom.
  IPR013575   IF2_assoc_dom_bac.
  IPR006847   IF2_N.
  IPR027417   P-loop_NTPase.
  IPR005225   Small_GTP-bd_dom.
  IPR000178   TF_IF2_bacterial-like.
  IPR015760   TIF_IF2.
  IPR023115   TIF_IF2_dom3.
  IPR009000   Transl_B-barrel.
  IPR004161   Transl_elong_EFTu/EF1A_2.
  PF00009   GTP_EFTU.
  PF03144   GTP_EFTU_D2.
  PF11987   IF-2.
  PF08364   IF2_assoc.
  PF04760   IF2_N.
  PS01176   IF2.