※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GTP cyclohydrolase 1
Protein Synonyms/Alias
 GTP-CH-I
Gene Name
 folE
Gene Synonyms/Alias
 b2153, JW2140
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
136 KDSVIGLSKINRIVQ S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; Allostericenzyme; Completeproteome; Directproteinsequencing; GTP-binding; Hydrolase; Metal-binding; Nucleotide-binding; One-carbonmetabolism; Referenceproteome; Zinc
Protein Sequence
 MPSLSKEAAL VHEALVARGL ETPLRPPVHE MDNETRKSLI AGHMTEIMQL LNLDLADDSL 60
 METPHRIAKM YVDEIFSGLD YANFPKITLI ENKMKVDEMV TVRDITLTST CEHHFVTIDG 120
 KATVAYIPKD SVIGLSKINR IVQFFAQRPQ VQERLTQQIL IALQTLLGTN NVAVSIDAVH 180
 YCVKARGIRD ATSATTTTSL GGLFKSSQNT RHEFLRAVRH HN 222
  GO:0005737   C:cytoplasm IDA:EcoliWiki
  GO:0043234   C:protein complex IDA:EcoliWiki
  GO:0005525   F:GTP binding IDA:EcoliWiki
  GO:0003934   F:GTP cyclohydrolase I activity IDA:EcoCyc
  GO:0008270   F:zinc ion binding IDA:EcoCyc
  GO:0035998   P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process IEA:UniProtKB-UniPathway
  GO:0006730   P:one-carbon metabolic process IEA:UniProtKB-HAMAP
  GO:0008616   P:queuosine biosynthetic process IMP:EcoCyc
  GO:0046654   P:tetrahydrofolate biosynthetic process IEA:UniProtKB-HAMAP
  IPR001474   GTP_CycHdrlase_I.
  IPR018234   GTP_CycHdrlase_I_CS.
  IPR020602   GTP_CycHdrlase_I_dom.
  PF01227   GTP_cyclohydroI.
  PS00859   GTP_CYCLOHYDROL_1_1.
  PS00860   GTP_CYCLOHYDROL_1_2.