UniProt Accession

 EFTS_ECOLI;  P0A6P1;  P02997

Genbank Protein ID

 V00343;  D13334;  U00096;  AP009048;  U70214

Genbank Nucleotide ID

 CAA23632.1;  BAA02597.1;  AAC73281.1;  BAB96746.1;  AAB08599.1

Protein Name

 Elongation factor Ts

Protein Synonyms/Alias

 EF-Ts

Gene Name

 tsf

Gene Synonyms/Alias

 b0170, JW0165

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
 Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M
 Mol. Cell Proteomics 2008, Feb;7(2):299-307. [PMID:17938405]
 [2]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]

Functional Description From UniProt

 FUNCTION: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

Sequence Annotation From UniProt

 

Key Word From UniProt

 3D-structure; Completeproteome; Cytoplasm; Directproteinsequencing; Elongationfactor; Proteinbiosynthesis; Referenceproteome

Protein Sequence

  GO:0005737   C:cytoplasm IDA:UniProtKB
  GO:0016020   C:membrane IDA:UniProtKB
  GO:0005085   F:guanyl-nucleotide exchange factor activity IDA:EcoCyc
  GO:0003746   F:translation elongation factor activity IEA:UniProtKB-HAMAP
  GO:0008270   F:zinc ion binding IDA:EcoliWiki
  GO:0043087   P:regulation of GTPase activity IDA:GOC

  IPR001816   Transl_elong_EFTs/EF1B.
  IPR014039   Transl_elong_EFTs/EF1B_dimer.
  IPR018101   Transl_elong_Ts_CS.
  IPR009060   UBA-like.
  IPR000449   UBA/Ts_N.

  PF00889   EF_TS.
  PF00627   UBA.

  PS01126   EF_TS_1.
  PS01127   EF_TS_2.