Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphocarrier protein HPr |
Protein Synonyms/Alias | |
Gene Name | ptsH |
Gene Synonyms/Alias | lmo1002 |
Created Date | 3-June-2014 |
Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) |
NCBI Taxa ID | 169963 |
Phosphorylation | Position | Peptide | Code | Type | References | 12 | SFVVIDETGIHARPA | T | HTP | [1] | 68 | ITIYTEGSDEKEAIE | S | HTP | [1] | 52 | KSIMGVMSLGIGKGA | S | HTP | [1] | 46 | GKKVNLKSIMGVMSL | S | HTP | [1] | 27 | TLLVQAASKYSSDVQ | S | HTP | [1] | |
Reference | [1]Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence. Misra SK,Milohanic E,Aké F,Mijakovic I,Deutscher J,Monnet V,Henry C Proteomics 2011, Nov;11(21):4155-65. [ PMID:21956863] |
Functional Description From UniProt | FUNCTION: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III) |
| MOD_RES 46 46 Phosphoserine; by HPrK/P (By similarity) |
| Completeproteome; Cytoplasm; Kinase; Phosphoprotein; Phosphotransferasesystem; Referenceproteome; Serine/threonine-proteinkinase; Sugartransport; Transcription; Transcriptionregulation; Transferase; Transport |
Protein Sequence | MEQASFVVID ETGIHARPAT LLVQAASKYS SDVQIEYTGK KVNLKSIMGV MSLGIGKGAD 60 ITIYTEGSDE KEAIEGLTEV LKKEGLAE 88 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0004674 F:protein serine/threonine kinase activity IEA:UniProtKB-KW GO:0005351 F:sugar:hydrogen symporter activity IEA:InterPro GO:0009401 P:phosphoenolpyruvate-dependent sugar phosphotransferase system IEA:UniProtKB-KW GO:0006355 P:regulation of transcription, DNA-templated IEA:UniProtKB-KW GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
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