※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphocarrier protein HPr
Protein Synonyms/Alias
 
Gene Name
 ptsH
Gene Synonyms/Alias
 BSU13900
Created Date
 3-June-2014
Organism
 Bacillus subtilis (strain 168)
NCBI Taxa ID
 224308
Phosphorylation
Position
Peptide
Code
Type
References
25 PATVLVQTASKYDAD T HTP [1]
27 TVLVQTASKYDADVN S HTP [1]
9 AQKTFKVTADSGIHA T HTP [1]
12 TFKVTADSGIHARPA S HTP [1],UniProt
20 GIHARPATVLVQTAS T HTP [1]
15 VTADSGIHARPATVL H HTP [1],UniProt
52 KSIMGVMSLGIAKGA S HTP [1]
46 GKTVNLKSIMGVMSL S HTP [2],UniProt
Reference
 [1]The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
 Macek B,Mijakovic I,Olsen JV,Gnad F,Kumar C,Jensen PR,Mann M
 Mol. Cell Proteomics 2007, Apr;6(4):697-707. [PMID:17218307]
 [2]Dynamics of protein phosphorylation on Ser/Thr/Tyr in Bacillus subtilis.
 Eymann C,Becher D,Bernhardt J,Gronau K,Klutzny A,Hecker M
 Proteomics 2007, Oct;7(19):3509-26. [PMID:17726680]
Functional Description From UniProt
 FUNCTION: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III)
Sequence Annotation From UniProt
 MOD_RES 12 12 Phosphoserine
 MOD_RES 15 15 Tele-phosphohistidine; alternate
 MOD_RES 46 46 Phosphoserine; by HPrK/P
Key Word From UniProt
 3D-structure; Completeproteome; Cytoplasm; Directproteinsequencing; Kinase; Phosphoprotein; Phosphotransferasesystem; Referenceproteome; Serine/threonine-proteinkinase; Sugartransport; Transcription; Transcriptionregulation; Transferase; Transport
Protein Sequence
 MAQKTFKVTA DSGIHARPAT VLVQTASKYD ADVNLEYNGK TVNLKSIMGV MSLGIAKGAE 60
 ITISASGADE NDALNALEET MKSEGLGE 88
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0004674   F:protein serine/threonine kinase activity IEA:UniProtKB-KW
  GO:0005351   F:sugar:hydrogen symporter activity IEA:InterPro
  GO:0009401   P:phosphoenolpyruvate-dependent sugar phosphotransferase system IEA:UniProtKB-KW
  GO:0043610   P:regulation of carbohydrate utilization IMP:CACAO
  GO:0006355   P:regulation of transcription, DNA-templated IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR000032   HPr_prot-like.
  IPR001020   PTS_HPr_His_P_site.
  IPR002114   PTS_HPr_Ser_P_site.
  PF00381   PTS-HPr.
  PS51350   PTS_HPR_DOM.
  PS00369   PTS_HPR_HIS.
  PS00589   PTS_HPR_SER.
  PR00107   PHOSPHOCPHPR.