| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphate regulon sensor protein PhoR |
Protein Synonyms/Alias | |
Gene Name | phoR |
Gene Synonyms/Alias | nmpB; OrderedLocusNames=b0400, JW0390 |
Created Date | 3-June-2014 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Phosphorylation | Position | Peptide | Code | Type | References | | 213 | NFFANVSHELRTPLT | H | LTP | [1] | |
Reference | [1]The narX and narL genes encoding the nitrate-sensing regulators of Escherichia coli are homologous to a family of prokaryotic two-component regulatory genes. Nohno T,Noji S,Taniguchi S,Saito T Nucleic Acids Res. 1989, Apr, 25;17(8):2947-57. [ PMID:2657652] |
Functional Description From UniProt | FUNCTION: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals |
| TRANSMEM 10 28 Helical; (Probable)
TRANSMEM 33 51 Helical; (Probable)
MOD_RES 213 213 Phosphohistidine; by autocatalysis (By similarity) |
| ATP-binding; Cellinnermembrane; Cellmembrane; Completeproteome; Kinase; Membrane; Nucleotide-binding; Phosphatetransport; Phosphoprotein; Referenceproteome; Transferase; Transmembrane; Transmembranehelix; Transport; Two-componentregulatorysystem |
Protein Sequence | MLERLSWKRL VLELLLCCLP AFILGAFFGY LPWFLLASVT GLLIWHFWNL LRLSWWLWVD 60
RSMTPPPGRG SWEPLLYGLH QMQLRNKKRR RELGNLIKRF RSGAESLPDA VVLTTEEGGI 120
FWCNGLAQQI LGLRWPEDNG QNILNLLRYP EFTQYLKTRD FSRPLNLVLN TGRHLEIRVM 180
PYTHKQLLMV ARDVTQMHQL EGARRNFFAN VSHELRTPLT VLQGYLEMMN EQPLEGAVRE 240
KALHTMREQT QRMEGLVKQL LTLSKIEAAP THLLNEKVDV PMMLRVVERE AQTLSQKKQT 300
FTFEIDNGLK VSGNEDQLRS AISNLVYNAV NHTPEGTHIT VRWQRVPHGA EFSVEDNGPG 360
IAPEHIPRLT ERFYRVDKAR SRQTGGSGLG LAIVKHAVNH HESRLNIEST VGKGTRFSFV 420
IPERLIAKNS D 431 |
| GO:0016021 C:integral component of membrane IDA:EcoCyc GO:0005886 C:plasma membrane IDA:EcoCyc GO:0005524 F:ATP binding IEA:UniProtKB-KW GO:0004721 F:phosphoprotein phosphatase activity IMP:EcoCyc GO:0000155 F:phosphorelay sensor kinase activity IDA:EcoCyc GO:0016036 P:cellular response to phosphate starvation IEP:EcoCyc GO:0016311 P:dephosphorylation IMP:GOC GO:0006817 P:phosphate ion transport IEA:UniProtKB-KW GO:0000160 P:phosphorelay signal transduction system IDA:EcoCyc GO:0046777 P:protein autophosphorylation IDA:EcoCyc GO:0006355 P:regulation of transcription, DNA-templated IEA:InterPro GO:0023014 P:signal transduction by phosphorylation IDA:GOC |
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