| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Thymidine phosphorylase |
Protein Synonyms/Alias | |
Gene Name | deoA |
Gene Synonyms/Alias | tpp, ttg; OrderedLocusNames=b4382, JW4345 |
Created Date | 3-June-2014 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Phosphorylation | Position | Peptide | Code | Type | References | | 157 | GVAIIGQTSSLAPAD | T | HTP | [1] | |
Reference | [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium. Soares NC,Spät P,Krug K,Macek B J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [ PMID:23590516] |
Functional Description From UniProt | FUNCTION: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis |
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| 3D-structure; Completeproteome; Glycosyltransferase; Referenceproteome; Transferase |
Protein Sequence | MFLAQEIIRK KRDGHALSDE EIRFFINGIR DNTISEGQIA ALAMTIFFHD MTMPERVSLT 60
MAMRDSGTVL DWKSLHLNGP IVDKHSTGGV GDVTSLMLGP MVAACGGYIP MISGRGLGHT 120
GGTLDKLESI PGFDIFPDDN RFREIIKDVG VAIIGQTSSL APADKRFYAT RDITATVDSI 180
PLITASILAK KLAEGLDALV MDVKVGSGAF MPTYELSEAL AEAIVGVANG AGVRTTALLT 240
DMNQVLASSA GNAVEVREAV QFLTGEYRNP RLFDVTMALC VEMLISGKLA KDDAEARAKL 300
QAVLDNGKAA EVFGRMVAAQ KGPTDFVENY AKYLPTAMLT KAVYADTEGF VSEMDTRALG 360
MAVVAMGGGR RQASDTIDYS VGFTDMARLG DQVDGQRPLA VIHAKDENNW QEAAKAVKAA 420
IKLADKAPES TPTVYRRISE 440 |
| GO:0016020 C:membrane IDA:UniProtKB GO:0004645 F:phosphorylase activity IEA:InterPro GO:0016154 F:pyrimidine-nucleoside phosphorylase activity IEA:InterPro GO:0009032 F:thymidine phosphorylase activity IDA:EcoCyc GO:0006974 P:cellular response to DNA damage stimulus IEP:EcoliWiki GO:0006206 P:pyrimidine nucleobase metabolic process IEA:InterPro GO:0006213 P:pyrimidine nucleoside metabolic process IEA:InterPro |
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