※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peptide chain release factor 2
Protein Synonyms/Alias
 RF-2
Gene Name
 prfB
Gene Synonyms/Alias
 supK; OrderedLocusNames=b2891, JW5847
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
169 KTEIIEESEGEVAGI S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Sequence Annotation From UniProt
 MOD_RES 252 252 N5-methylglutamine
Key Word From UniProt
 3D-structure; Completeproteome; Cytoplasm; Directproteinsequencing; Methylation; Proteinbiosynthesis; Referenceproteome; Ribosomalframeshifting
Protein Sequence
 MFEINPVNNR IQDLTERSDV LRGYLDYDAK KERLEEVNAE LEQPDVWNEP ERAQALGKER 60
 SSLEAVVDTL DQMKQGLEDV SGLLELAVEA DDEETFNEAV AELDALEEKL AQLEFRRMFS 120
 GEYDSADCYL DIQAGSGGTE AQDWASMLER MYLRWAESRG FKTEIIEESE GEVAGIKSVT 180
 IKISGDYAYG WLRTETGVHR LVRKSPFDSG GRRHTSFSSA FVYPEVDDDI DIEINPADLR 240
 IDVYRTSGAG GQHVNRTESA VRITHIPTGI VTQCQNDRSQ HKNKDQAMKQ MKAKLYELEM 300
 QKKNAEKQAM EDNKSDIGWG SQIRSYVLDD SRIKDLRTGV ETRNTQAVLD GSLDQFIEAS 360
 LKAGL 365
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0016149   F:translation release factor activity, codon specific IDA:EcoCyc
  GO:0006415   P:translational termination IDA:EcoCyc
  IPR014720   dsRNA-bd_dom.
  IPR005139   PCRF.
  IPR000352   Pep_chain_release_fac_I_II.
  IPR020853   Peptide_chain_release_fac2_bac.
  IPR004374   PrfB.
  PF03462   PCRF.
  PF00472   RF-1.
  SM00937   PCRF.
  PS00745   RF_PROK_I.