Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional regulator AppY |
Protein Synonyms/Alias | |
Gene Name | appY |
Gene Synonyms/Alias | b0564, JW0553 |
Created Date | 3-June-2014 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Phosphorylation | Position | Peptide | Code | Type | References | 201 | KLITSNSYSINVVAQ | Y | HTP | [1] | 202 | LITSNSYSINVVAQK | S | HTP | [1] | |
Reference | [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence. Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A PLoS Pathog. 2013;9(6):e1003403. [ PMID:23785281] |
Functional Description From UniProt | FUNCTION: Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions |
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| Completeproteome; DNA-binding; Referenceproteome; Repressor; Transcription; Transcriptionregulation |
Protein Sequence | MDYVCSVVFI CQSFDLIINR RVISFKKNSL FIVSDKIRRE LPVCPSKLRI VDIDKKTCLS 60 FFIDVNNELP GKFTLDKNGY IAEEEPPLSL VFSLFEGIKI ADSHSLWLKE RLCISLLAMF 120 KKRESVNSFI LTNINTFTCK ITGIISFNIE RQWHLKDIAE LIYTSESLIK KRLRDEGTSF 180 TEILRDTRMR YAKKLITSNS YSINVVAQKC GYNSTSYFIC AFKDYYGVTP SHYFEKIIGV 240 TDGINKTID 249 |
| GO:0043565 F:sequence-specific DNA binding IEA:InterPro GO:0003700 F:sequence-specific DNA binding transcription factor activity IDA:EcoCyc GO:0016036 P:cellular response to phosphate starvation IDA:EcoCyc GO:0045893 P:positive regulation of transcription, DNA-templated IDA:EcoCyc GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
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