| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Beta-lactamase |
Protein Synonyms/Alias | |
Gene Name | ampC |
Gene Synonyms/Alias | ampA; OrderedLocusNames=b4150, JW4111 |
Created Date | 3-June-2014 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Phosphorylation | Position | Peptide | Code | Type | References | | 80 | QTLFELGSVSKTFTG | S | HTP | [1] | |
Reference | [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M Mol. Cell Proteomics 2008, Feb;7(2):299-307. [ PMID:17938405] |
Functional Description From UniProt | FUNCTION: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins |
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| 3D-structure; Antibioticresistance; Completeproteome; Directproteinsequencing; Hydrolase; Periplasm; Referenceproteome; Signal |
Protein Sequence | MFKTTLCALL ITASCSTFAA PQQINDIVHR TITPLIEQQK IPGMAVAVIY QGKPYYFTWG 60
YADIAKKQPV TQQTLFELGS VSKTFTGVLG GDAIARGEIK LSDPTTKYWP ELTAKQWNGI 120
TLLHLATYTA GGLPLQVPDE VKSSSDLLRF YQNWQPAWAP GTQRLYANSS IGLFGALAVK 180
PSGLSFEQAM QTRVFQPLKL NHTWINVPPA EEKNYAWGYR EGKAVHVSPG ALDAEAYGVK 240
STIEDMARWV QSNLKPLDIN EKTLQQGIQL AQSRYWQTGD MYQGLGWEML DWPVNPDSII 300
NGSDNKIALA ARPVKAITPP TPAVRASWVH KTGATGGFGS YVAFIPEKEL GIVMLANKNY 360
PNPARVDAAW QILNALQ 377 |
| GO:0030288 C:outer membrane-bounded periplasmic space IEA:InterPro GO:0008800 F:beta-lactamase activity IDA:EcoliWiki GO:0017001 P:antibiotic catabolic process IEA:InterPro GO:0046677 P:response to antibiotic IEA:UniProtKB-KW |
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