※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative ribosome biogenesis GTPase RsgA
Protein Synonyms/Alias
 
Gene Name
 rsgA
Gene Synonyms/Alias
 engC, yloQ; OrderedLocusNames=BSU15780
Created Date
 3-June-2014
Organism
 Bacillus subtilis (strain 168)
NCBI Taxa ID
 224308
Phosphorylation
Position
Peptide
Code
Type
References
166 IPHFQDKTTVFAGQS T LTP [1]
Reference
 [1]Phosphorylation of CpgA protein enhances both its GTPase activity and its affinity for ribosome and is crucial for Bacillus subtilis growth and morphology.
 Pompeo F,Freton C,Wicker-Planquart C,Grangeasse C,Jault JM,Galinier A
 J. Biol. Chem. 2012, Jun, 15;287(25):20830-8. [PMID:22544754]
Functional Description From UniProt
 FUNCTION: Depletion of yloQ results in sensitization towards protein synthesis inhibitors that block the peptide channel or peptidyl transferase center on the ribosome, implying that YloQ functions in conjunction with the ribosome in vivo. Decreasing levels of YloQ lead to an increase in unassembled 30S and 50S subunit and a decrease in the assembled 70S ribosome
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; Completeproteome; GTP-binding; Hydrolase; Metal-binding; Nucleotide-binding; Referenceproteome; Zinc
Protein Sequence
 MPEGKIIKAL SGFYYVLDES EDSDKVIQCR GRGIFRKNKI TPLVGDYVVY QAENDKEGYL 60
 MEIKERTNEL IRPPICNVDQ AVLVFSAVQP SFSTALLDRF LVLVEANDIQ PIICITKMDL 120
 IEDQDTEDTI QAYAEDYRNI GYDVYLTSSK DQDSLADIIP HFQDKTTVFA GQSGVGKSSL 180
 LNAISPELGL RTNEISEHLG RGKHTTRHVE LIHTSGGLVA DTPGFSSLEF TDIEEEELGY 240
 TFPDIREKSS SCKFRGCLHL KEPKCAVKQA VEDGELKQYR YDHYVEFMTE IKDRKPRY 298
  GO:0005525   F:GTP binding IEA:UniProtKB-HAMAP
  GO:0003924   F:GTPase activity IEA:UniProtKB-HAMAP
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  IPR010914   EngC_GTPase.
  IPR012340   NA-bd_OB-fold.
  IPR027417   P-loop_NTPase.
  IPR004881   Ribosome_biogen_GTPase_RsgA.
  PF03193   DUF258.
  PS50936   ENGC_GTPASE.