※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine--tRNA ligase
Protein Synonyms/Alias
 SerRS
Gene Name
 serS
Gene Synonyms/Alias
 SSO0602; ORFNames=C08_048
Created Date
 3-June-2014
Organism
 Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
NCBI Taxa ID
 273057
Phosphorylation
Position
Peptide
Code
Type
References
437 VPKVLRKYLEAFPKA Y HTP [1]
Reference
 [1]Change of carbon source causes dramatic effects in the phospho-proteome of the archaeon Sulfolobus solfataricus.
 Esser D,Pham TK,Reimann J,Albers SV,Siebers B,Wright PC
 J. Proteome Res. 2012, Oct, 5;11(10):4823-33. [PMID:22639831]
Functional Description From UniProt
 FUNCTION: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Aminoacyl-tRNAsynthetase; ATP-binding; Completeproteome; Cytoplasm; Ligase; Nucleotide-binding; Proteinbiosynthesis; Referenceproteome
Protein Sequence
 MSWSILELLR KNPEDLKNNL KRRAIDVSLV DKAVELDKKW RQVLQEVEKL RHQHNVLSSQ 60
 ISKLSGEERK KKIEESKNLL KILEEKEKEL EEIENERDRL LSSLPNLVAD DVPNGPDDSY 120
 NVPIKFWGKF KVYEGDVQEF LKQIKDAKVN YEVIKWKPKG HAEMLEDVLH LGNTLKAAEI 180
 AGSRFYYLFN DIVWLDFSLL LFAIDYITQQ GYTLVLPPYM LRGEVIQSVI DLDTFKDAIY 240
 KIENEDLYLI ATAEHPIAAM FFKEEIEKDK LPLKFAGISP AFRKEASAAN KDLKGIFRVH 300
 QFHKVEQFIF STPEDSWKYH SELITNAESI FQQLELPYRI VNIASGDLGA CAAKKFDLEV 360
 WMPAQAKFRE MVSCSNCTDW QAFRMKIRYV DRKNNRRGYV HTLNSTAIAS TRTITAILEN 420
 YQREDGVVEV PKVLRKYLEA FPKAPKDYIY PLKNKII 457
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0004828   F:serine-tRNA ligase activity IEA:UniProtKB-HAMAP
  GO:0016260   P:selenocysteine biosynthetic process IEA:UniProtKB-HAMAP
  GO:0097056   P:selenocysteinyl-tRNA(Sec) biosynthetic process IEA:UniProtKB-UniPathway
  GO:0006434   P:seryl-tRNA aminoacylation IEA:UniProtKB-HAMAP
  IPR002314   aa-tRNA-synt_IIb_cons-dom.
  IPR006195   aa-tRNA-synth_II.
  IPR002317   Ser-tRNA-ligase_type_1.
  IPR015866   Ser-tRNA-synth_1_N.
  IPR010978   tRNA-bd_arm.
  PF02403   Seryl_tRNA_N.
  PF00587   tRNA-synt_2b.
  PS50862   AA_TRNA_LIGASE_II.
  PR00981   TRNASYNTHSER.